Evidence map›Paper›PMID 40270504›Full record

ArticleFrontiers in medicine2025

Nomogram risk prediction model for acute respiratory distress syndrome following acute kidney injury.

Hui Lin, Yilin Ren, Jing Cui, Junnan Guo, Mengzhu Wang, Lihua Wang, Xiaole Su, Xi Qiao

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hui Lin *Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Yilin Ren *Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Jing Cui *Department of Endocrinology, Air Force Medical Center, Beijing, China.
Junnan GuoDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Mengzhu WangDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Lihua WangDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Xiaole SuDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.
Xi QiaoDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute respiratory distress syndrome (ARDS), a severe form of respiratory failure, can be precipitated by acute kidney injury (AKI), leading to a significant increase in mortality among affected patients. This study aimed to identify the risk factors for ARDS and construct a predictive nomogram. Methods: We conducted a retrospective analysis of 1,241 AKI patients admitted to the Second Hospital of Shanxi Medical University from August 25, 2016, to December 31, 2023. The patients were divided into a study cohort (1,012 cases, including 108 with ARDS) and a validation cohort (229 cases, including 23 with ARDS). Logistic regression analysis was employed to identify the risk factors for ARDS, which were subsequently incorporated into the development of a nomogram. The predictive performance of the nomogram was assessed by AUC, calibration plots, and decision curve analyses, with external validation also performed. Results: Six risk factors were identified and included in the nomogram: older age (OR = 1.020; 95%CI = 1.005-1.036), smoking history (OR = 1.416; 95%CI = 1.213-1.811), history of diabetes mellitus (OR = 1.449; 95%CI = 1.202-1.797), mean arterial pressure (MAP; OR = 1.165; 95%CI = 1.132-1.199), higher serum uric acid levels (OR = 1.002; 95%CI = 1.001-1.004), and higher AKI stage [(stage 1: reference), (stage 2: OR = 11.863; 95%CI = 4.850-29.014), (stage 3: OR = 41.398; 95%CI = 30.840-52.731)]. The AUC values were 0.951 in the study cohort and 0.959 in the validation cohort. Calibration and decision curve analyses confirmed the accuracy and clinical utility of the nomogram. Conclusion: The nomogram, which integrates age, smoking history, diabetes mellitus history, MAP, and AKI stage, predicts the risk of ARDS in patients with AKI. This tool may aid in early detection and facilitate clinical decision-making.

Indexed as

acute kidney injury (AKI)acute respiratory distress syndrome (ARDS)early predictionnomogramrisk factor

Identifiers

PMID40270504
PMCPMC12014638

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.