ArticleFrontiers in public health2025
Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Greater temporo-occipital gray matter volume and frontoparietal cortical thickness in post-menopausal women: a UK Biobank study.Brain structure & function · 2026Article
- Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives.Neural regeneration research · 2026Article
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- rAAV production cost analysis: Indication-specific cost per dose and reduction strategies.Gene therapy · 2026Article
- Calcineurin/NFAT signaling in the temporal integration of Ca²⁺ stress in neurodegeneration.Cell death discovery · 2026Review
- Diverging trends in motor neuron disease burden in China: an ageing-driven increase despite declining age-standardised rates - a GBD 2021 analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- New Discoveries in the Field of Neuropharmacology.Biomolecules · 2026Article
- Migraine and menopause as converging factors in brain vulnerability: a hypothesis-driven perspective.The journal of headache and pain · 2026Review
- The Burden of Multiple Sclerosis in Japan from 1990 to 2021 and Predictions to 2050 Based on the Global Burden of Disease Study 2021.Neuroepidemiology · 2026Article
- The Endocannabinoid-Microbiota-Neuroimmune Super-System: A Unifying Feedback Architecture for Systems Resilience, Collapse Trajectories, and Precision Feedback Medicine.International journal of molecular sciences · 2025Review
- Artificial Intelligence-Driven Neuromodulation in Neurodegenerative Disease: Precision in Chaos, Learning in Loss.Biomedicines · 2025Review
- Molecular mechanisms of neuroprotective effect of rutin.Frontiers in pharmacology · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Background: The burden of neurological diseases in women is underestimated. This study aimed to estimate the pattern and trend of four major nervous system diseases in women. Methods: Utilizing data from the GBD Study 2021 on the incidence and disability-adjusted life-years (DALYs) of Alzheimer's disease (AD) and other dementias, Parkinson's disease, multiple sclerosis, and idiopathic epilepsy in women from 1990 to 2021. We estimated trends by age and socio-demographic index (SDI), globally, regionally, and nationally, using Estimated annual percentage changes (EAPC), Spearman correlation analysis and projected future trends with the Bayesian age-period-cohort (BAPC) model. Results: In 2021, an estimated 6191564.2, 572999.9, 1536118.7, and 39191.7 new cases of female AD and other dementias, Parkinson's disease, multiple sclerosis, and idiopathic epilepsy were reported globally, with a significant increase in age-standardized incidence rate (ASIR) from 1990 to 2021. Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. AD and other dementias and Parkinson's disease were prevalent among women worldwide, followed by idiopathic epilepsy and multiple sclerosis, with regional and country disparities. There are also difference of patterns among age and SDI. The BAPC model projects that by 2050, the ASIR of the four major neurological disorders will continue to increase. Conclusion: The burden of major neurological diseases in women is a serious global health challenge. Given the regional disparities and varying age patterns in incidence and DALYs, there is an urgent need for tailored prevention and healthcare approaches to mitigate the burden worldwide.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.