Evidence map›Paper›PMID 40271273›Full record

ArticleJournal of education and health promotion2025

Association between SARS-CoV-2 viral load and serum biomarkers with mortality in Mexican patients.

Dulce M Razo-Blanco-Hernández, José Á Hernández-Mariano, Mónica A Díaz-Cureño, Lenny Navarrete-Martínez, Juan C Bravata-Alcántara, Roberto Rivera-Sanchez, Verónica Fernandez-Sánchez

Abstract read
In one paragraph

Article in Journal of education and health promotion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dulce M Razo-Blanco-HernándezDepartment of Research, Hospital Juarez of Mexico, CDMX, Mexico.
José Á Hernández-MarianoDepartment of Research, Hospital Juarez of Mexico, CDMX, Mexico.
Mónica A Díaz-CureñoDepartment of Medical Research and Teaching, Hospital Juárez de México, CDMX, Mexico.
Lenny Navarrete-MartínezDepartment of Institutional Development and Outreach, Hospital Juárez de México, CDMX, Mexico.
Juan C Bravata-AlcántaraDepartment of Citogenetics, Hospital Juarez of Mexico, CDMX, Mexico.
Roberto Rivera-SanchezDepartment of Research, Hospital Juarez of Mexico, CDMX, Mexico.
Verónica Fernandez-SánchezDepartment of Research, Hospital Juárez de México, CDMX, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) pandemic has resulted in high mortality among hospitalized patients; thus, identifying mortality markers in treating these patients is essential. To evaluate the association between viral load and serum biomarkers with mortality among hospitalized patients with COVID-19. MATERIALS AND

methodsA retrospective cohort study was conducted among 198 inpatient records from a tertiary hospital in Mexico City between January and April 2021. The association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load and serum biomarkers with death due to COVID-19 was assessed using Cox regression models.

resultsThe median age was 54.9 years, and 61.6% were males. The mortality rate was 43.4%. After adjusting for potential confounders, patients with higher viral load [adjusted hazard ratio (aHR) = 1.56; 95% confidence interval (95% CI) = 1.01, 2.42;

conclusionSARS-CoV-2 viral load and serum biomarkers such as BUN, creatinine, glucose, osmolarity, and lymphocytes could help physicians identify individuals who require closer monitoring.

Indexed as

BiomarkersCOVID-19mortalitySARS-CoV-2viral load

Identifiers

PMID40271273
PMCPMC12017452

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.