Evidence map›Paper›PMID 40271336›Full record

ArticleCureus2025

Comparing No-Code Platforms and Deep Learning Models for Glaucoma Detection From Fundus Images.

Mauro Gobira, Luis F Nakayama, Caio Vinicius S Regatieri, Rubens Belfort

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mauro GobiraOphthalmology, Vision Institute - Instituto Paulista de Estudos e Pesquisas em Oftalmologia (IPEPO), São Paulo, BRA.
Luis F NakayamaOphthalmology, Universidade Federal de São Paulo (UNIFESP), São Paulo, BRA.
Caio Vinicius S RegatieriOphthalmology, Universidade Federal de São Paulo (UNIFESP), São Paulo, BRA.
Rubens BelfortOphthalmology, Universidade Federal de São Paulo (UNIFESP), São Paulo, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study compares the performance of two no-code machine learning platforms, Google's Teachable Machine (TM) (Google LLC, Mountain View, CA, USA) and Apple's Create ML (Apple Inc., Cupertino, CA, USA), alongside a traditional deep learning model, ResNet200d, in classifying optic nerve fundus images into glaucoma and non-glaucoma categories using the ACRIMA dataset.

methodsA comparative cross-sectional analysis was conducted using 705 labeled fundus images from the ACRIMA dataset (326 glaucomatous, 239 non-glaucomatous). Models were trained separately on each platform, and a validation set comprising 70 glaucomatous and 70 non-glaucomatous images was used to assess performance. Performance metrics, such as sensitivity, specificity, F1 score, and Cohen's kappa, were assessed with 95% confidence intervals. Statistical analysis was performed using DATAtab (DATAtab e.U. Graz, Austria (https://datatab.net)).

resultsThe ResNet200d model demonstrated the highest performance, with an accuracy of 99.29%, a sensitivity of 98.57%, a specificity of 100%, and an F1 score of 99.29%. Create ML achieved a sensitivity of 93.24%, a specificity of 98.48%, and an F1 score of 95.83%. TM exhibited a sensitivity of 95.71%, a specificity of 94.29%, and an F1 score of 95.04%. Both no-code platforms demonstrated strong performance, with Create ML excelling in specificity and TM showing higher sensitivity.

conclusionWhile the ResNet200d model outperformed both no-code platforms in diagnostic accuracy, the no-code platforms demonstrated robust capabilities, highlighting their potential to democratize artificial intelligence (AI) in healthcare. These results highlight the potential of no-code platforms for democratizing medical image analysis, especially in resource-limited contexts. Further studies with diverse datasets are recommended to validate these results.

Indexed as

acrima datasetcreate mldeep learningfundus imagesglaucoma detectionresnet200dteachable machine

Identifiers

PMID40271336
PMCPMC12015992

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.