Evidence map›Paper›PMID 40272754›Full record

SynthesisObesity surgery2025

Gastro-Oesophageal Reflux Disease Outcomes Following Roux-en-Y Gastric Bypass Surgery in Patients with Obesity: A Systematic Review and Meta-analysis.

Narek Sargsyan, Iihan Ali, Christopher Namgoong, Bibek Das, Matyas Fehervari, Michael G Fadel

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Narek SargsyanDepartment of Surgery and Cancer, Imperial College London, London, UK.
Iihan AliFaculty of Medicine, Imperial College London, London, UK.
Christopher NamgoongFaculty of Medicine, Imperial College London, London, UK.
Bibek DasDepartment of Surgery and Cancer, Imperial College London, London, UK.
Matyas Fehervari *Department of Surgery and Cancer, Imperial College London, London, UK.
Michael G Fadel *Department of Surgery and Cancer, Imperial College London, London, UK. m.fadel@imperial.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to investigate the effect of primary Roux-en-Y gastric bypass (RYGB) on gastro-oesophageal reflux disease (GORD) in patients with obesity. A systematic review was performed using MEDLINE, Embase, Emcare, and CINAHL databases for studies that reported on GORD outcomes following RYGB for obesity (January 2000-November 2023). Fourteen studies with 28,027 patients underwent RYGB, with pooled analysis demonstrating a 47% (95% CI 34.0-59.0; p ≤ 0.005) improvement in GORD symptoms and 4.5% (95% CI 1.7-7.2; p ≤ 0.005) with worsening/new onset GORD. Postoperative DeMeester score improved by 16.49 points (95% CI 0.2-32.7; p ≤ 0.005) and 79.4% (95% CI 68.7-90.1; p = 0.01) completely discontinued proton-pump inhibitor therapy during the follow-up period. RYGB surgery may potentially improve GORD symptoms in patients with obesity, with an overall low incidence of de novo GORD.

Indexed as

Gastric BypassGastroesophageal RefluxObesityObesity, MorbidHumansProton Pump InhibitorsTreatment OutcomeProton Pump InhibitorsBariatric surgeryGastric bypassGastro-oesophageal reflux diseaseObesityOutcomes

Identifiers

PMID40272754
PMCPMC12130072

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.