ArticleRenal failure2025
Association of insulin resistance indices with kidney stones and their recurrence in a non-diabetic population: an analysis based on NHANES data from 2007-2018.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between the triglyceride-glucose index and kidney stone disease: a systematic review and dose-response meta-analysis.Lipids in health and disease · 2026Pooled it
- Article
- Obesity, Metabolic Syndrome, Diabetes and Kidney Stones: Strengthening Links Over Time?TouchREVIEWS in endocrinology · 2026Review
- Nonlinear association between estimated glucose disposal rate and kidney stones: a cross-sectional study.The Canadian journal of urology · 2026Article
- Article
- Obesity-Related Insulin Resistance Indices and CKD Risk in Patients with Diabetes and Coronary Heart Disease: A Multicenter Cohort Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Association between estimated glucose disposal rate and the risk of atherosclerotic cardiovascular disease: insight from cross-sectional and retrospective cohort studies.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically evaluate the association between insulin resistance indices and the risk of kidney stones and their recurrence in U.S. non-diabetic individuals, while identifying predictive indicators. MATERIALS AND
methodsThis cross-sectional study analyzed data from the 2007-2018 NHANES. Five IR indices were calculated. Weighted logistic regression, restricted cubic spline, and mediation analyses were used to assess the independent associations between these indices and the risk of kidney stones and recurrence in non-diabetic individuals.
resultThis study of 9,605 non-diabetic participants showed an overall kidney stones incidence of 8.63% and a recurrence rate of 2.70%. Weighted logistic regression and RCS analyses revealed significant positive associations between METs-IR, HOMA-IR, TyG-BMI, and the risk of kidney stones and their recurrence. Every unit increase in METs-IR was linked to a 2% rise in the incidence of kidney stones (95% CI: 1.014-1.027,
conclusionThis study found that elevated IR indices (METs-IR, HOMA-IR, TyG-BMI) significantly increased kidney stone risk in a non-diabetic population. Serum uric acid and vitamin D mediated this association, with METs-IR best predicting kidney stones incidence and recurrence.
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