Evidence map›Paper›PMID 40275692›Full record

ArticleJournal of rehabilitation medicine2025

Cost-effectiveness of cognitive behavioural therapy versus health education for sleep disturbance and fatigue following stroke and traumatic brain injury.

Duncan Mortimer, Lucy Ymer, Adam McKay, Dana Wong, Kate Frencham, Natalie Grima, Monique Roper, Sylvia Nguyen, Jade Murray, Gershon Spitz and 1 more

Abstract readComparative Study
In one paragraph

Article in Journal of rehabilitation medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Duncan MortimerCentre for Health Economics, Monash Business School, Monash University, Melbourne, VIC, Australia. duncan.mortimer@monash.edu.
Lucy YmerMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Adam McKayMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia.
Dana WongMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.
Kate FrenchamMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Natalie GrimaMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Monique RoperMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Sylvia NguyenEpworth Healthcare, Melbourne, VIC, Australia.
Jade MurrayMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Gershon SpitzMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.
Jennie PonsfordMonash Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate cost, effectiveness and cost-effectiveness of cognitive behavioural therapy for sleep and fatigue (CBT-SF) vs health education (HE) and of CBT-SF vs treatment as usual (TAU) for sleep disturbance and fatigue in acquired brain injury.

designEconomic evaluation from Australian health system and societal perspectives based on data from a June 2017 to October 2023 randomized controlled trial. SUBJECTS: Community-dwelling Australian adults with sleep disturbance and fatigue following acquired brain injury (n = 126).

methodsIncremental health system costs based on cost of delivery and health service utilization since last follow-up. Incremental effectiveness based on participant-reported sleep quality, fatigue, and quality of life at each timepoint. Productivity gains/losses based on a 1-week activity diary at each timepoint.

resultsReductions in health service utilization from CBT-SF (-A$777, 95% CI: -A$4,232, A$2,678) offset higher delivery costs (A$333, 95% CI: A$109, A$556) relative to HE, with improvements in quality of life at 2 months post-treatment (0.02, 95% CI: -0.01, 0.05) and an additional 3.37 quality-adjusted life days per participant (95% CI: -4.18, 10.92). CBT-SF dominates HE (less costly and more effective) and is likely more cost-effective than HE (66-76%). CBT-SF is cost-effective relative to TAU under realistic assumptions.

conclusionsCBT-SF after acquired brain injury improved clinical and economic outcomes and was more likely to be cost-effective than HE. Further research is required to precisely estimate the cost-effectiveness of CBT-SF vs TAU and to demonstrate generalizability to routine practice and other settings. ANZCTR Trial registration numbers: 1261700087830; 12617000879369.

Indexed as

Brain Injuries, TraumaticCognitive Behavioral TherapyFatigueHealth EducationSleep Wake DisordersStrokeAdultAgedAustraliaCost-Benefit AnalysisFemaleHumansMaleMiddle AgedQuality of LifeRandomized Controlled Trials as Topic

Identifiers

PMID40275692
PMCPMC12041795

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.