ReviewFrontiers in cardiovascular medicine2025
The power of the left atrioventricular coupling index in cardiovascular disease.
Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Article
- Diagnostic and prognostic value of left atrioventricular coupling index post revascularization in acute coronary syndrome: A two-dimensional echocardiographic study.Clinical physiology and functional imaging · 2026Article
- Left Atrioventricular Coupling Index: A Comprehensive Review of the Literature.Life (Basel, Switzerland) · 2026Review
- Femoral Plaque Burden and Left Ventricular-Arterial Coupling in Patients with Chronic Heart Failure.Journal of clinical medicine · 2026Article
- Left Atrioventricular Coupling Index Predicts Poor Prognosis in Acute Myocardial Infarction: A Single-Center Cohort Study.Journal of cardiovascular development and disease · 2026Article
- Echocardiographic assessment of left atrioventricular coupling index: technical approaches and clinical implementation strategies.Frontiers in cardiovascular medicine · 2026Review
- Prognostic impact of cardiovascular magnetic resonance-derived left atrioventricular coupling Index in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.European heart journal. Imaging methods and practice · 2026Article
- The predictive value of left atrioventricular coupling index for ILR-detected atrial fibrillation following an embolic stroke of undetermined source in patients with sinus rhythm.European heart journal. Imaging methods and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The left atrioventricular coupling index (LACI) has emerged as a novel and transformative biomarker in cardiovascular research, addressing long-standing limitations in traditional cardiac function assessments. By quantifying the ratio of left atrial to left ventricular end-diastolic volumes, LACI offers unprecedented prognostic insights into a wide range of cardiovascular diseases, including atrial fibrillation, heart failure, and myocardial infarction, as well as other conditions such as hypertension and cardiomyopathies. Recent evidence highlights its unique ability to integrate atrial and ventricular dynamics, offering a more comprehensive perspective on cardiac health and disease progression. This review synthesizes the latest advancements in LACI research, elucidates its underlying pathophysiological mechanisms, and explores its expanding clinical applications as a pivotal tool for risk stratification, precision diagnostics, and personalized therapy in cardiovascular medicine.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.