Evidence map›Paper›PMID 40276521›Full record

ReviewCraniomaxillofacial trauma & reconstruction2025

Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.

Chun Ho Hung, Yui Chit Kwok, Jason Yip, Ho Hin Wong, Yiu Yan Leung

Abstract readReview
In one paragraph

Review in Craniomaxillofacial trauma & reconstruction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chun Ho HungOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).ORCID https://orcid.org/0009-0001-4825-4865
Yui Chit KwokOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).
Jason YipOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).
Ho Hin WongOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).
Yiu Yan LeungOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).ORCID https://orcid.org/0000-0002-6670-6570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study was to evaluate the clinical outcomes, safety, and clinical applications of bioabsorbable magnesium-based materials for fixation in bone surgeries. The review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. An initial search was performed on electronic databases, followed by manual and reference searches. The articles selected were evaluated for patient characteristics, biocompatibility, the need for revision surgery, bone union rates, and the incidence of gas formation associated with implant degradation. Out of the 631 initially identified articles, 8 studies including a total of 386 patients were included in the final qualitative analysis. The magnesium (Mg) group carried a lower rate of revision surgery (1/275) when compared to the titanium (Ti) group (18/111). A high rate of bone union was found in the Mg group and a low infection rate (3/275) was found in the Mg group. The serum level of Mg and calcium (Ca) were not found to be affected. Mg implants are applied in various orthopedic surgeries but they are not applied in in oral or maxillofacial surgeries. Mg implants appear to be a safe alternative for bone fixation and are resorbable. Future research into the application of Mg implants in bone fixation in different anatomical sites is essential to fully harness their potential benefits for patients.

Indexed as

absorbablebone surgeryfixationmagnesiumosteosynthesis

Identifiers

PMID40276521
PMCPMC12015880

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.