Evidence map›Paper›PMID 40276584›Full record

ArticleAquaculture nutrition2025

Effects of Low Molecular Weight Duck Blood Protein Hydrolysate as a Feed Additive on the Intestinal Microbiome, Antioxidant Activity, and Humoral Immune and Inflammatory Responses in Flowerhorn Fish.

Pimpisut Manassila, Papungkorn Sangsawad, Surintorn Boonanuntanasarn, Jirawadee Kaewda, Pakpoom Boonchuen, Sirawich Limkul, Chatsirin Nakharuthai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aquaculture nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pimpisut ManassilaSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0009-0000-4794-3813
Papungkorn SangsawadSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0003-2420-8634
Surintorn BoonanuntanasarnSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0002-1690-3664
Jirawadee KaewdaSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0009-0009-7036-0531
Pakpoom BoonchuenSchool of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0002-1896-1139
Sirawich LimkulSchool of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0002-5158-8858
Chatsirin NakharuthaiSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0001-6165-2940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food-derived bioactive peptides could serve as feed ingredients and/or feed additives. We investigated the health-promoting properties of low molecular weight duck blood protein hydrolysate (DBPH), fractionated by ultrafiltration with a 10 kDa molecular weight cut-off membrane, in flowerhorn fish. The analysis of molecular weight distribution revealed that the most common sizes of DBPH fell within the range of 3-7 kDa (39.68%), followed by >7-10 kDa (20.69%), 1-3 kDa (23.03%), and <1 kDa (9.00%). After 1 month of the feeding trial, fish fed with diets supplemented with 2% DBPH exhibited the highest growth, antioxidant activity, and humoral immune response enhancement under normal conditions. In addition, microbiome analysis confirmed that 2% DBPH possesses antimicrobial activity, as evidenced by the significant decrease in operational taxonomic units (OTUs) and alpha diversity indexes, including Chao1 and Shannon. Compared to the control group, fish that were fed with diets supplemented with 2% DBPH exhibited a significantly higher abundance of the genera Cetobacterium and Romboutsia, which could serve as indicators of the overall health and well-being of the fish. After a

Indexed as

antioxidantduck bloodimmune responsemicrobiomeprotein hydrolysate

Identifiers

PMID40276584
PMCPMC12021490

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.