SynthesisJournal of clinical ultrasound : JCU2025
Application of Two-Dimensional Shear Wave Elastography in Evaluating Liver Reserve Function in Patients With Liver Cancer.
Synthesis in Journal of clinical ultrasound : JCU, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Application of Two-Dimensional Shear Wave Elastography in Evaluating Liver Reserve Function in Patients With Liver Cancer.Journal of clinical ultrasound : JCU · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundShear wave elastography (SWE) is an emerging noninvasive imaging technique for assessing liver fibrosis. This meta-analysis aimed to evaluate the diagnostic accuracy of SWE compared to conventional imaging techniques.
methodsA systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science databases. Nine studies were included, and diagnostic performance metrics, including sensitivity, specificity, diagnostic odds ratio (DOR), and area under the receiver operating characteristic curve (AUC), were pooled using meta-analysis. Publication bias was assessed using Deeks' funnel plot asymmetry test.
resultsThe pooled sensitivity and specificity of SWE were 0.88 (95% CI: 0.83-0.92) and 0.88 (95% CI: 0.83-0.91), respectively. The positive likelihood ratio (PLR) was 7.07 (95% CI: 5.26-9.50), and the negative likelihood ratio (NLR) was 0.14 (95% CI: 0.09-0.20). The DOR was 51.85 (95% CI: 29.80-90.19), and the area under the SROC curve (AUC) was 0.94 (95% CI: 0.91-0.96), indicating excellent diagnostic accuracy. Fagan nomogram analysis further confirmed SWE's clinical utility by significantly improving post-test probability. No significant publication bias was detected (p = 0.26).
conclusionSWE is a highly accurate and reliable tool for diagnosing liver fibrosis, demonstrating superior diagnostic performance compared to conventional imaging techniques. SWE has significant potential to serve as a noninvasive alternative to liver biopsy in the clinical assessment of liver fibrosis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.