Evidence map›Paper›PMID 40277091›Full record

ReviewMovement disorders : official journal of the Movement Disorder Society2025

Corticospinal Tract Development, Evolution, and Skilled Movements.

Emmanuel Roze, Caroline Dubacq, Quentin Welniarz

Abstract readReview
In one paragraph

Review in Movement disorders : official journal of the Movement Disorder Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emmanuel RozeSorbonne Université, INSERM, CNRS, Paris Brain Institute Institut du Cerveau, Paris, France.
Caroline DubacqSorbonne Université, INSERM, CNRS, Paris Brain Institute Institut du Cerveau, Paris, France.
Quentin WelniarzSorbonne Université, INSERM, CNRS, Paris Brain Institute Institut du Cerveau, Paris, France.ORCID https://orcid.org/0000-0001-6051-1142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of the corticospinal tract (CST) is closely linked to the development of skilled voluntary movements in mammals. The main evolutionary divergence concerns the position of the CST within the spinal cord white matter and its postsynaptic targets in the grey matter. Here, we examine the developmental steps contributing to the CST projection pattern from an evolutionary point of view. Recent studies have highlighted the molecular mechanisms involved in these processes and how they relate to the acquisition of skilled movements. Comparison of the evolution of the CST in different species offers a new perspective on manual dexterity. In particular, it adds a new level of complexity to the classic view linking the evolution of the CST and the sequential improvement of skilled hand movements from rodents to primates. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Biological EvolutionMotor SkillsPyramidal TractsAnimalsHumansaxon guidancecortico‐motoneuronal connectionmammalian evolutionmotor systemvoluntary movement

Identifiers

PMID40277091
PMCPMC12273621

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.