Evidence map›Paper›PMID 40277573›Full record

ReviewBiosensors2025

Challenges of Using Whole-Cell Bioreporter for Assessment of Heavy Metal Bioavailability in Soil/Sediment.

Shanshan Bai, Zhipeng Liu, Jiazhi Xu, Yongshuo Li, Zirun Zhang, Zefeng Huang, Williamson Gustave, Boling Li, Xiaokai Zhang, Feng He

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shanshan BaiInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Zhipeng LiuInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Jiazhi XuInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Yongshuo LiInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Zirun ZhangInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Zefeng HuangInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Williamson GustaveSchool of Chemistry, Environmental & Life Sciences, University of the Bahamas, Nassau 4912, Bahamas.
Boling LiSchool of Environmental Science and Engineering, Suzhou University of Science and Technology, Suzhou 215123, China.
Xiaokai ZhangInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.
Feng HeInstitute of Environmental Processes and Pollution Control, School of Environment and Ecology, Jiangnan University, Wuxi 214122, China.

Funding

Fundamental Research Funds for the Central University JUSRP202407001National Natural Science Foundation of China 42477518
6 · The paper itself

Abstract

Soil and sediment contamination with heavy metals (HMs) is a critical environmental issue, posing significant risks to both ecosystems and human health. Whole-cell bioreporter (WCB) technology offers a promising alternative to traditional detection techniques due to its ability to rapidly assess the bioavailability of pollutants. Specifically, lights-on WCBs quantify pollutant bioavailability by measuring bioluminescence or fluorescence in response to pollutant exposure, demonstrating comparable accuracy to traditional methods for quantitative pollutant detection. However, when applied to soil and sediment, the signal intensity directly measured by WCBs is often attenuated due to interference from solid particles, leading to the underestimation of bioavailability. Currently, no standardized method exists to correct for this signal attenuation. This review provides a critical analysis of the benefits and limitations of traditional detection methods and WCB technology in assessing HM bioavailability in soil and sediment. Based on the approaches used to address WCB signal attenuation, correction methods are categorized into four types: the assumed negligible method, the non-inducible luminescent control method, the addition of a standard to a reference soil, and a pre-exposure bioreporter. We provide a comprehensive analysis of each method's applicability, benefits, and limitations. Lastly, potential future directions for advancing WCB technology are proposed. This review seeks to establish a theoretical foundation for researchers and environmental professionals utilizing WCB technology for pollutant bioavailability assessment in soil and sediment.

Indexed as

Biosensing TechniquesEnvironmental MonitoringGeologic SedimentsMetals, HeavySoilSoil PollutantsBiological AvailabilityHumansMetals, HeavySoilSoil Pollutantsbioluminescencebiosensorenvironmental risk assessmentsignal transmissionsoil pollution

Identifiers

PMID40277573
PMCPMC12025839

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.