Evidence map›Paper›PMID 40281232›Full record

Trial reportEuropean journal of applied physiology2025

Vascular adaptations to blood flow restriction resistance training with different cuff types: the role of retrograde shear stress.

Lin-Sheng Chen, Natalie McLaurin, Philippe Brosselin, Daniela Charry, Taha Alhalimi, Hirofumi Tanaka

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lin-Sheng ChenDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA.
Natalie McLaurinDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA.
Philippe BrosselinDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA.
Daniela CharryDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA.
Taha AlhalimiDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA.
Hirofumi TanakaDepartment of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd, D3700, Austin, TX, 78712, USA. htanaka@austin.utexas.edu.ORCID http://orcid.org/0000-0002-1780-7471

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNarrow-elastic bands (NE) and wide-rigid cuffs (WR) are two types of cuffs that are frequently used in blood flow restriction (BFR) training. Because these cuffs produce different hemodynamic responses, vascular adaptations might differ depending upon what cuffs are used. We examined the hypothesis that BFR with NE would improve vascular function while BFR with WR would decrease vascular function.

methodsTwenty-six young healthy participants completed supervised BFR training for 2 weeks with NE placed on one arm and WR on the other arm during upper-body resistance exercise using random arm allocation with counterbalancing across the participants. Flow-mediated dilation (FMD), arterial stiffness, muscle strength, and muscle mass in both arms were measured before and after the intervention. To explore possible mechanisms underlying vascular adaptations, retrograde shear rates (SR) induced by different cuffs in the brachial artery were also measured before the intervention.

resultsMuscle strength increased in both arms (p < 0.05). FMD increased in the NE arm (5.6 ± 2.9 to 7.7 ± 3.4%, p = 0.004) but did not change in the WR arm (6.0 ± 2.5 to 4.9 ± 2.7%, p = 0.12). Retrograde SR was higher under WR occlusion compared with NE occlusion and no cuff (no cuff: 22 ± 9, NE: 25 ± 9 vs. WR: 39 ± 13 s

conclusionDifferent BFR cuffs led to similar muscle adaptations but different vascular adaptations. The difference in the vascular adaptation between two different cuffs might be explained by a greater retrograde SR induced by WR occlusion.

Indexed as

Adaptation, PhysiologicalBlood Flow Restriction TherapyResistance TrainingAdultBrachial ArteryFemaleHumansMaleMuscle, SkeletalMuscle StrengthRegional Blood FlowVascular StiffnessYoung AdultArterial stiffnessFlow-mediated dilationKaatsu trainingMuscle strengthPulse wave velocity

Identifiers

PMID40281232

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.