Evidence map›Paper›PMID 40281983›Full record

ArticleAnimals : an open access journal from MDPI2025

Effects of Embryonic Thermal Manipulation on Body Performance and Cecum Microbiome in Broiler Chickens Following a Post-Hatch Lipopolysaccharide Challenge.

Seif Hundam, Mohammad Borhan Al-Zghoul, Mustafa Ababneh, Lo'ai Alanagreh, Rahmeh Dahadha, Mohammad Mayyas, Daoud Alghizzawi, Minas A Mustafa, David E Gerrard, Rami A Dalloul

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seif HundamDepartment of Basic Medical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0009-0009-6943-5225
Mohammad Borhan Al-ZghoulDepartment of Basic Medical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-4404-2889
Mustafa AbabnehDepartment of Basic Medical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-3725-1471
Lo'ai AlanagrehDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa 13133, Jordan.ORCID 0000-0001-5759-4581
Rahmeh DahadhaDepartment of Basic Medical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Mohammad MayyasDepartment of Animal Production, Faculty of Agriculture, Jordan University of Science and Technology, Irbid 22110, Jordan.
Daoud AlghizzawiDepartment of Basic Medical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0009-0001-1001-7215
Minas A MustafaDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa 13133, Jordan.ORCID 0009-0007-7960-0007
David E GerrardSchool of Animal Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.ORCID 0000-0002-3482-1400
Rami A DalloulDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0003-4690-9220

Funding

Deanship of Research at Jordan University of Science and Technology 188/2019 and 400/2024
6 · The paper itself

Abstract

Thermal manipulation (TM) during embryogenesis has emerged as a promising strategy to enhance post-hatch performance and improve resilience to environmental and bacterial stress, which offers a potential alternative to reduce the reliance on antibiotic growth promoters (AGPs) in broiler production. This study investigated TM's ability to modulate broilers' cecal microbiota and enhance resilience to lipopolysaccharide (LPS)-induced stress. Eggs in the control group (CON) were incubated at 37.8 °C and 56% relative humidity (RH), while TM eggs were exposed to 39 °C and 65% RH for 18 h daily from embryonic days 10-18. Post-hatch, the LPS subgroups (LPS-CON, LPS-TM) received intraperitoneal LPS injections, and body weight (BW) and temperature (BT) were monitored. Cecal samples were collected for microbiome sequencing. Alpha diversity showed no differences (

Indexed as

antimicrobialbroilergut healthlipopolysaccharidemicrobiomethermal manipulation

Identifiers

PMID40281983
PMCPMC12024374

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.