Evidence map›Paper›PMID 40282012›Full record

ArticleAnimals : an open access journal from MDPI2025

Genetic Architecture of Hock Joint Bumps in Pigs: Insights from ROH and GWAS Analyses.

Lyubov Getmantseva, Maria Kolosova, Varvara Shevtsova, Anatoly Kolosov, Faridun Bakoev, Elena Romanets, Timofey Romanets, Siroj Bakoev

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PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lyubov GetmantsevaBiotechnological Faculty, Don State Agrarian University, Persianovsky 346493, Russia.
Maria KolosovaBiotechnological Faculty, Don State Agrarian University, Persianovsky 346493, Russia.ORCID 0000-0003-2979-7108
Varvara ShevtsovaSouthern Scientific Centre of the Russian Academy of Sciences, Rostov-on-Don 344006, Russia.
Anatoly KolosovAll Russian Research Institute of Animal Breeding, Lesnye Polyany 141212, Russia.ORCID 0000-0002-6583-8942
Faridun BakoevBiotechnological Faculty, Don State Agrarian University, Persianovsky 346493, Russia.
Elena RomanetsBiotechnological Faculty, Don State Agrarian University, Persianovsky 346493, Russia.ORCID 0000-0003-2824-9564
Timofey RomanetsBiotechnological Faculty, Don State Agrarian University, Persianovsky 346493, Russia.
Siroj BakoevAll Russian Research Institute of Animal Breeding, Lesnye Polyany 141212, Russia.

Funding

Russian Science Foundation 22-76-10015
6 · The paper itself

Abstract

The genetic mechanisms underlying the formation of defects, such as bumps and growths on the hock joints in pigs, remain poorly understood. Therefore, the aim of this study was to investigate the relationship between runs of homozygosity (ROH) and the formation of hock joint bumps, with the goal of identifying associated SNPs and candidate genes involved in these defects. The study was conducted on a population of Large White breed pigs (n = 568) using runs of homozygosity (ROH) analysis and genome-wide association studies (GWAS). The results suggested that the predisposition to hock joint bumps in pigs may have arisen due to recent selective breeding pressure. Using GWAS, 27 SNPs were identified at the suggestive significance level, with one SNP (rs325478346) reaching genome-wide significance. These markers are localized in genes associated with various biological processes, including lipid metabolism (

Indexed as

GWASLarge White breedlegs defectspigsROHSNP

Identifiers

PMID40282012
PMCPMC12023961

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.