Evidence map›Paper›PMID 40282371›Full record

ArticleGenes2025

Identification of Candidate Genes and Functional Pathways Associated with Body Size Traits in Hulunbuir Sheep Through GWAS Analysis.

Hengqian Yang, Tingting Li, Na Zhang, Jieran Chen, Yuting Zhang, Shiyu Peng, Lisheng Zhou, Runlin Ma, Zhichao Zhang, Qiuyue Liu and 2 more

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hengqian YangCollege of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China.
Tingting LiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Na ZhangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Jieran ChenState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Yuting ZhangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0009-0003-8386-2908
Shiyu PengState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Lisheng ZhouCollege of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China.
Runlin MaState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Zhichao ZhangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Qiuyue LiuState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Haitao WangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Jianning HeCollege of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China.

Funding

Biological Breeding-National Science and Technology Major Project 2022ZD04013, 2023ZD0407106, 2023ZD0406805Integrated Application of Cost Reduction Technologies in Sheep Farms 20240140Strategic Priority Research Program of Chinese Academy of Sciences XDA26040303
6 · The paper itself

Abstract

(1) Background: The Hulunbuir sheep is a Chinese local sheep breed with good meat quality and exceptional cold-stress resilience. However, the growth performance of the Hulunbuir sheep is lower when compared to that of commercial breeds. Growth traits such as body weight and body size are critical, as they directly influence the meat production in sheep farming. Employing genome-wide association studies can identify SNPs and candidate genes related to growth traits in Hulunbuir sheep. (2) Methods: The chest girth (CG), cannon circumference (CC), hip width (HW), body height (BH), and body length (BL) of 799 Hulunbuir sheep were measured. All the animals were divided into three groups according to their age (Group 1: 0-6 months old, Group 2: 12-24 months old, Group 3: 48-70 months old). Subsequently, genotyping was carried out using the Sheep 40K liquid chip. A multi-trait genome-wide association study (MT-GWAS) was performed for each group of animals. (3) Results: A total of three candidate genes (

Indexed as

Body SizeGenome-Wide Association StudyAnimalsBreedingPhenotypePolymorphism, Single NucleotideQuantitative Trait, HeritableQuantitative Trait LociSheepbody sizecandidate genesGWASHulunbuir sheep

Identifiers

PMID40282371
PMCPMC12026710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.