Evidence map›Paper›PMID 40283092›Full record

ArticleLife (Basel, Switzerland)2025

The Use of the Masquelet Technique in the Treatment of Pathological Distal Third Femoral Fracture Secondary to Chronic Osteomyelitis.

Razvan Cosmin Tudor, Daniel Vasile Timofte, Norin Forna, Oana Viola Badulescu, Liliana Savin, Tudor Pinteala, Dan Mihailescu, Tudor Ciobotariu, Alin Ciobica, Mihnea Theodor Sirbu and 5 more

Abstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Razvan Cosmin TudorDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-2881-3527
Daniel Vasile TimofteDepartment of Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-6604-874X
Norin FornaDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-5637-2095
Oana Viola Badulescu"Sfantul Spiridon" Emergency County Clinical Hospital, 700111 Iasi, Romania.ORCID 0000-0001-7050-8430
Liliana SavinDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Tudor PintealaDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-7664-0918
Dan MihailescuDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Tudor CiobotariuFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Alin Ciobica"Ioan Haulica" Institute, Apollonia University, 700511 Iasi, Romania.
Mihnea Theodor SirbuDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Paul Dan SirbuDepartment of Orthopedics and Traumatology, Surgical Science (II), Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2806-0649
Serban DragosloveanuDepartment of Orthopaedics and Traumatology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7403-1684
Bogdan Sorin CapitanuDepartment of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.
Romica CerganDepartment of Anatomy, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Cristian ScheauDepartment of Radiology and Medical Imaging, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.ORCID 0000-0001-7676-6393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic osteomyelitis is a persistent infection of the bone that poses significant challenges, particularly when associated with pathological fractures and extensive bone defects. This case report highlights the application of Masquelet's induced membrane technique (MIMT) in managing a complex distal femur defect in a 50-year-old male with a long-standing history of chronic osteomyelitis. The patient presented with a non-union fracture, severe osseous destruction, and infection, requiring a multidisciplinary approach. CASE REPORT: The first stage involved radical debridement of necrotic tissue and stabilization with a titanium plate and an antibiotic-impregnated polymethylmethacrylate spacer to induce a bioactive membrane. The second stage, performed 30 days later, after infection resolution, entailed removing the spacer, harvesting an autologous iliac crest bone graft, and filling the defect within the preserved membrane. Postoperative care included a tailored antibiotic regimen and gradual weight-bearing, leading to favorable clinical and radiological outcomes.

conclusionsThis case demonstrates the utility of MIMT in reconstructing extensive bone defects while addressing infection. The technique provides a reliable and effective alternative to amputation, offering high success rates and functional restoration in complex cases.

Indexed as

imagingMasquelet techniqueosteomyelitispathological fracturesegmental defectstreatment

Identifiers

PMID40283092
PMCPMC12028495

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.