Evidence map›Paper›PMID 40283454›Full record

ReviewJournal of clinical medicine2025

The Role of Positron Emission Tomography Imaging in Primary Bone Tumours: A Narrative Review.

Shihabul Hassan, Rishabh Suvarna, Hasaam Uldin, Mohsin Hussein, Rajesh Botchu

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Primary malignant bone tumours-part 1].Radiologie (Heidelberg, Germany) · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shihabul HassanDepartment of General Medicine, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL, UK.
Rishabh SuvarnaSchool of Medicine, Worsely Building, University of Leeds, Leeds LS2 9JT, UK.
Hasaam UldinDepartment of Musculoskeletal Radiology, Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham B31 2AP, UK.ORCID 0000-0001-7060-211X
Mohsin HusseinDepartment of Radiology, University Hospitals of Leicester, Leicester LE2 7LX, UK.ORCID 0000-0003-4275-8699
Rajesh BotchuDepartment of Musculoskeletal Radiology, Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham B31 2AP, UK.ORCID 0000-0001-7998-2980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary malignant bone tumours can pose significant diagnostic and therapeutic challenges due to inter-tumour heterogeneity. While traditional imaging modalities such as radiography, MRI (magnetic resonance imaging), and CT (computed tomography) remain essential for initial evaluation and staging, emerging evidence underscores the evolving role of positron emission tomography (PET), particularly PET/CT with Fluorodeoxyglucose ([18F] FDG), in the comprehensive management of bone sarcomas. This narrative review aims to critically summarise the available literature on PET imaging's utility in the management of primary bone tumours including osteosarcoma, chondrosarcoma, and Ewing sarcoma. Despite limitations like inconsistencies in standard uptake value (SUV) cutoffs and reduced pulmonary resolution, PET/CT is valuable for staging, assessing response to neoadjuvant chemotherapy, predicting histological outcomes, detecting recurrence, and guiding biopsy in metabolically active tumour sites. Further large-scale, prospective studies are warranted to standardise protocols and establish PET's definitive role in sarcoma management.

Indexed as

bone neoplasmschondrosarcomaEwingfluorodeoxyglucose F18osteosarcomapositron emission tomography computed tomographysarcoma

Identifiers

PMID40283454
PMCPMC12027646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.