Evidence map›Paper›PMID 40283959›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood-Brain Barrier Obstacle?

Silvana Filieri, Morena Miciaccia, Domenico Armenise, Olga Maria Baldelli, Anselma Liturri, Savina Ferorelli, Anna Maria Sardanelli, Maria Grazia Perrone, Antonio Scilimati

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Mitochondrial Protease ClpP: Cancer Marker and Drug Target.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silvana FilieriDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, 70124 Bari, Italy.
Morena MiciacciaResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0002-0727-6435
Domenico ArmeniseResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0009-0002-7525-3910
Olga Maria BaldelliResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Anselma LiturriResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0009-0005-3291-8910
Savina FerorelliResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0001-6686-9364
Anna Maria SardanelliDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-8535-7601
Maria Grazia PerroneResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0003-4195-5228
Antonio ScilimatiResearch Laboratory for the Woman and Child Health, Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0003-2740-6425

Funding

HPC -"National Centre for HPC, Big Data and Quantum Computing - HPC" "Simulazioni, calcolo e analisi dei dati ad alte prestazioni CN000000013Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP), project MNESYS PE0000006PRIN: progetti di ricerca di rilevante interesse nazionale 2022WYFST2
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood–brain barrier (BBB)chemotherapydiffuse intrinsic pontine glioma (DIPG)DMG H3K27-alteredfocused ultrasound (FUS)radiotherapy (RT)

Identifiers

PMID40283959
PMCPMC12030708

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.