Evidence map›Paper›PMID 40284138›Full record

ReviewPlants (Basel, Switzerland)2025

Trans-Kingdom RNA Dialogues: miRNA and milRNA Networks as Biotechnological Tools for Sustainable Crop Defense and Pathogen Control.

Hui Jia, Pan Li, Minye Li, Ning Liu, Jingao Dong, Qing Qu, Zhiyan Cao

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Wheat miR408 and miR159 Weaken the Virulence ofPlants (Basel, Switzerland) · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui JiaState Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Baoding 071000, China.
Pan LiState Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Baoding 071000, China.
Minye LiCollege of Life Sciences, Fujian Normal University, Fuzhou 350117, China.
Ning LiuState Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Baoding 071000, China.ORCID 0000-0003-1806-1218
Jingao DongState Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Baoding 071000, China.
Qing QuCollege of Agriculture and Forestry, Hebei North University, Zhangjiakou 075000, China.
Zhiyan CaoState Key Laboratory of North China Crop Improvement and Regulation, Hebei Agricultural University, Baoding 071000, China.

Funding

Basic Scientific Research Expenses of Hebei Provincial Universities BSJJ202434the China Agriculture Research System CARS-02the National Natural Science Foundation of China 32402304the Science and Technology Project of the Hebei Education Department ZC2024006the S&T Program of Hebei 23567601H
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of non-coding RNAs approximately 20-24 nucleotides in length, which play a crucial role during gene regulation in plant-pathogen interaction. They negatively regulate the expression of target genes, primarily at the transcriptional or post-transcriptional level, through complementary base pairing with target gene sequences. Recent studies reveal that during pathogen infection, miRNAs produced by plants and miRNA-like RNAs (milRNAs) produced by fungi can regulate the expression of endogenous genes in their respective organisms and undergo trans-kingdom transfer. They can thereby negatively regulate the expression of target genes in recipient cells. These findings provide novel perspectives for deepening our understanding of the regulatory mechanisms underlying plant-pathogen interactions. Here, we summarize and discuss the roles of miRNAs and milRNAs in mediating plant-pathogen interactions via multiple pathways, providing new insights into the functions of these RNAs and their modes of action. Collectively, these insights lay a theoretical foundation for the targeted management of crop diseases.

Indexed as

endogenous regulationfungal milRNAplant miRNAplant–pathogen interactiontrans-kingdom regulation

Identifiers

PMID40284138
PMCPMC12030539

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.