Evidence map›Paper›PMID 40284160›Full record

ArticleNutrients2025

Blood DNA Methylation in Nuclear and Mitochondrial Sequences Links to Malnutrition and Poor Prognosis in ALS: A Longitudinal Study.

Antia Fernandez-Pombo, Andrea G Izquierdo, Ana Canton-Blanco, Tania Garcia-Sobrino, David Hervás, Miguel A Martínez-Olmos, Julio Pardo, Ana B Crujeiras

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Medical nutrition therapy for ALS: Dietitians' approaches to diagnosing malnutrition, facilitating feeding tube discussions, and mitigating refeeding syndrome risk.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antia Fernandez-PomboEpigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0002-1268-7538
Andrea G IzquierdoEpigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0002-0846-8834
Ana Canton-BlancoDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), University of Santiago de Compostela (USC), 15706 Santiago de Compostela, A Coruña, Spain.
Tania Garcia-SobrinoDepartment of Neurology, Complejo Hospitalario Universitario de Santiago (CHUS), 15706 Santiago de Compostela, A Coruña, Spain.
David HervásDepartment of Applied Statistics and Operational Research and Quality, Universitat Politècnica de València, 46022 Valencia, Valencia, Spain.ORCID 0000-0003-0635-4961
Miguel A Martínez-OlmosDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), University of Santiago de Compostela (USC), 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0002-3279-8091
Julio PardoDepartment of Neurology, Complejo Hospitalario Universitario de Santiago (CHUS), 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0001-8807-1310
Ana B CrujeirasEpigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0003-4392-0301

Funding

Instituto de Salud Carlos III CIBEROBNInstituto de Salud Carlos III CPII22/00008Instituto de Salud Carlos III JR23/00042Xunta de Galicia IN607B-20240301
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyotrophic Lateral SclerosisDNA MethylationDNA, MitochondrialMalnutritionAgedBiomarkersDisease ProgressionEpigenesis, GeneticFemaleHumansLongitudinal StudiesMaleMiddle AgedNutritional StatusOxidative StressPrognosisBiomarkersDNA, Mitochondrialamyotrophic lateral sclerosisblood leukocytesD-loopepigeneticsGlobal Leadership Initiative on Malnutritionmalnutritionmitoepigeneticsprognosis

Identifiers

PMID40284160
PMCPMC12030252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.