Evidence mapPaperPMID 40284201Full record

ArticleNutrients2025

Taste Plasticity in Nutrition and Health: A Scoping Review.

Hayeon Sung, Elizabeth Heaton, Monica Dus

Abstract readScoping Review
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hayeon SungDepartment of Molecular, Cellular, and Developmental Biology, The University of Michigan College of Literature, Science, and the Arts, Ann Arbor, MI 48103, USA.
Elizabeth HeatonDepartment of Molecular, Cellular, and Developmental Biology, The University of Michigan College of Literature, Science, and the Arts, Ann Arbor, MI 48103, USA.
Monica DusDepartment of Molecular, Cellular, and Developmental Biology, The University of Michigan College of Literature, Science, and the Arts, Ann Arbor, MI 48103, USA.ORCID 0000-0003-1465-9028

Funding

Pilot and Feasibility ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2022 to 2025
$4.9M
Multidisciplinary Training Program in Basic Diabetes ResearchT32DK101357 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$416k
Neural determinants on meal size in invertebrate models of obesityR01DK130875 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$353k
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK130875NIH HHS 1DP2DK113750NIH HHS R01DK130875NIH HHS T32DK101357NSF CAREER 1941822The Rita Allen Foundation N/A
6 · The paper itself

Abstract

Taste sensation is at the intersection of nutrition and health. Our food choices are shaped by the foods we like, but our dietary habits can, in turn, influence how we sense food. This phenomenon, known as diet-induced taste plasticity, has received renewed attention as a tool for designing healthier foods and retraining eating habits. This review synthesizes emerging data from humans and model organisms to characterize how dietary environments shape taste sensation while exploring its underlying molecular and physiological mechanisms. Although there is still so much to discover about this phenomenon, accumulating evidence suggests an inverse relationship between a tastant concentration and the ability of the organism to respond to it. The effects largely depend on diet, but body weight changes play a role in specific dietary settings. Several mechanisms are at play, including receptor abundance and function, neuroendocrine signaling, gene expression, and neuroinflammation. Many open questions on mechanisms remain, including the concentration and times of exposure for effects to manifest and the consequences for nutrition and health. Beyond mechanisms, future research should explore strategies to leverage taste adaptation for healthier food design.

Indexed as

DietFeeding BehaviorNutritional Physiological PhenomenaNutritional StatusTasteTaste PerceptionAnimalsFood PreferencesHumansdietary effectsGLP-1 agonistsnutritionobesitypublic healthtaste plasticity

Identifiers

PMID40284201
PMCPMC12030297

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.