Evidence map›Paper›PMID 40284550›Full record

ArticleMicroorganisms2025

Induction of Immune Responses in Mice and Newborn Piglets by Oral Immunization with Recombinant

Xiulei Cai, Zhikui Wang, Xinping Yan, Xu Wang, Xiaoxue Yue, Hongliang Zhang

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiulei CaiCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.ORCID 0000-0001-9928-9999
Zhikui WangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.
Xinping YanCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.
Xu WangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.
Xiaoxue YueCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.
Hongliang ZhangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.ORCID 0000-0002-4184-896X

Funding

Shandong Provincial Key Research and Development Program(Major Scientific and Technological Innovation Project) NO.2023CXGC010705
6 · The paper itself

Abstract

Porcine epidemic diarrhea (PED) is a severe gastrointestinal disease caused by the porcine epidemic diarrhea virus (PEDV), a virus that spreads through the intestinal tract, leading to significant economic losses in the global swine industry. Therefore, compared to traditional injection method, developing vaccines that effectively stimulate the mucosal immune system to induce a protective immune response is crucial for PED prevention. This study evaluated the immunogenicity of recombinant

Indexed as

immunogenicity evaluationLactococcus lactismice and pigletsoral immunizationporcine epidemic diarrhea virus

Identifiers

PMID40284550
PMCPMC12029974

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.