Evidence map›Paper›PMID 40285010›Full record

ArticleViruses2025

Investigation of Hepatitis C, D, and HIV Seroprevalence and Evaluation of APRI and FIB-4 Scores in HbsAg-Positive Patients.

Fatih Mehmet Akıllı, Elif Nur Özbay Haliloğlu, Mehmet Mücahit Güncü, Dilara Turan Gökçe

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatih Mehmet AkıllıDepartment of Microbiology, Sincan Training and Research Hospital, Ankara 06930, Türkiye.ORCID 0000-0001-8541-7742
Elif Nur Özbay HaliloğluDepartment of Infectious Diseases and Clinical Microbiology, Sincan Training and Research Hospital, Ankara 06930, Türkiye.
Mehmet Mücahit GüncüDepartment of Microbiology, Marmara University Institute of Health Sciences, Istanbul 34854, Türkiye.
Dilara Turan GökçeDepartment of Gastroenterology, Sincan Training and Research Hospital, Ankara 06930, Türkiye.ORCID 0000-0003-3660-7237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the prevalence of HDV (hepatitis delta virus), HCV (hepatitis C virus), and HIV (human immunodeficiency virus) coinfections among HBsAg-positive patients and to determine the severity of liver fibrosis and biochemical markers. Furthermore, the study sought to evaluate the noninvasive fibrosis scores (APRI and FIB4) in predicting the severity of liver disease in patients with hepatitis B. A retrospective analysis of 1434 patients with chronic HBV admitted between January 2020 and December 2024 was conducted at Sincan Tertiary Hospital. The positivity rates of the following antibodies were the focus of the study: anti-HDV, anti-HCV, and anti-HIV. In addition to these, the levels of HIV-RNA, HCV-RNA and HBV-DNA, as well as several biochemical markers (ALT, AST, INR, albumin, bilirubin and platelet count) were also evaluated. The APRI and FIB-4 scores were calculated. Of the 1434 patients, 49 (3.4%) tested positive for anti-HDV, 784 were screened for anti-HCV, and 749 were screened for anti-HIV. The positivity rates were 3.4% (27/784) and 3.4% (26/749), respectively. According to ROC analysis, the FIB-4 score had a statistically significant effect on predicting anti-HDV negativity (AUC = 0.59,

Indexed as

Hepatitis B Surface AntigensHepatitis CHepatitis DHIV InfectionsAdultAgedBiomarkersCoinfectionFemaleHepacivirusHepatitis Delta VirusHumansLiver CirrhosisMaleMiddle AgedPrevalenceBiomarkersHepatitis B Surface Antigenscoinfectioneliminationepidemiologyliver fibrosisnoninvasive scoresseroprevalencevaccinationviral hepatitis

Identifiers

PMID40285010
PMCPMC12031327

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.