Evidence map›Paper›PMID 40285396›Full record

ArticleEuropean journal of pain (London, England)2025

Temporal Associations of Physical Activity With Subsequent Knee Pain in Individuals With Knee Osteoarthritis: An Ecological Momentary Assessment Study.

Alison H Chang, Emma Hertel, Malene Kjær Bruun, Erika Maria Kristensen, Kristian Kjær-Staal Petersen, Michael Skovdal Rathleff

Abstract read
In one paragraph

Article in European journal of pain (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alison H ChangDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.ORCID https://orcid.org/0000-0001-7309-9687
Emma HertelDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Malene Kjær BruunDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Erika Maria KristensenDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Kristian Kjær-Staal PetersenDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Michael Skovdal RathleffDepartment of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity (PA) is a first-line treatment for knee osteoarthritis and provides benefits for functional improvement and pain relief. However, movement-evoked pain often hinders PA participation and long-term adherence. The relationship between PA and pain is not fully understood and may vary across individuals. We examined the temporal associations between PA and subsequent knee pain in individuals with knee osteoarthritis.

methodsIn a 10-day ecological momentary assessment (EMA) cohort study, PA was recorded using an Actigraph accelerometer; momentary knee pain intensity was rated on a numeric rating scale in responses to four daily text prompts. Linear mixed-effects models examined within-day and between-day associations between PA and knee pain, adjusting for age, sex and BMI.

resultsThe sample included up to 454 observations across 10 days from 17 participants (age = 64 ± 7 years, BMI = 27 ± 4 kg/m

conclusionsWhile MVPA may temporarily increase knee pain, its impact was transient. Light-intensity PA showed no association with pain, suggesting it may be a suitable alternative for those with movement-evoked pain. Understanding these temporal patterns can help guide tailored pain management and PA adherence strategies. Further research is needed to confirm these preliminary findings. SIGNIFICANCE STATEMENT: Understanding the dynamic relationship between PA and knee pain is crucial for optimising the management of knee OA. This exploratory study offers new insights by leveraging high-frequency data to examine the intra- and inter-day associations of MVPA and light-intensity PA with subsequent knee pain. The preliminary findings demonstrate that MVPA may lead to transient pain increases, while light-intensity PA is not associated with pain intensity. Identifying these PA-pain temporal patterns can inform personalised strategies for pain management and improving long-term activity adherence.

Indexed as

ArthralgiaExerciseOsteoarthritis, KneeAccelerometryAgedCohort StudiesEcological Momentary AssessmentFemaleHumansKnee JointMaleMiddle AgedPain Measurementaccelerometerecological momentary assessmentknee osteoarthritisknee painphysical activitytemporal associations

Identifiers

PMID40285396
PMCPMC12032517

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.