Evidence map›Paper›PMID 40285645›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Red Blood Cell-Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell-Depleted Thrombi, Restoring Severe Bacteremia in Rats.

Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H Kang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bong Hwan JangDepartment of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology (UNIST), UNIST gil 50, Ulsan, 44919, Republic of Korea.ORCID https://orcid.org/0000-0001-6458-9692
Su Hyun JungDepartment of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology (UNIST), UNIST gil 50, Ulsan, 44919, Republic of Korea.ORCID https://orcid.org/0000-0002-9892-1400
Seyong KwonDepartment of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology (UNIST), UNIST gil 50, Ulsan, 44919, Republic of Korea.
Sung Jin ParkDepartment of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology (UNIST), UNIST gil 50, Ulsan, 44919, Republic of Korea.ORCID https://orcid.org/0000-0002-1476-9940
Joo H KangDepartment of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology (UNIST), UNIST gil 50, Ulsan, 44919, Republic of Korea.ORCID https://orcid.org/0000-0001-9636-3209

Funding

Korea Evaluation Institute of Industrial Technology, Ministry of Trade Industry & Energy RS-2024-00432382Korean Fund for Regenerative Medicine, Ministry of Science and ICT, the Ministry of Health & Welfare) 22A0102L1-11National Research Foundation of Korea, Ministry of Science and ICT RS-2024-00344187National Research Foundation of Korea, Ministry of Science and ICT RS-2024-00399800
6 · The paper itself

Abstract

Extracorporeal hemoadsorption for treating bacteremia has exhibited limited success due to the lack of a clear strategy for effectively bringing bacterial cells into contact with the surface and universal bacteria-capturing substances. Here, a novel extracorporeal device is reported that can eliminate various intact bacteria from whole blood, employing microfluidic bacterial margination and engineered cell-depleted thrombus (CDT) presenting bacterial adhesin receptors. The critical strain rate of red blood cells (RBCs) (0.83 × 10

Indexed as

BacteremiaErythrocytesThrombosisAnimalsHumansMaleRatsRats, Sprague-Dawleybacteremiabacterial adhesin receptorsbacterial marginationblood cell‐depleted thrombusextracorporeal blood cleansingsepsis treatment

Identifiers

PMID40285645
PMCPMC12362807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.