Evidence map›Paper›PMID 40286006›Full record

ArticleMolecules (Basel, Switzerland)2025

Lignin as a Bioactive Additive in Chlorzoxazone-Loaded Pharmaceutical Tablets.

Andreea Creteanu, Gabriela Lisa, Cornelia Vasile, Maria-Cristina Popescu, Daniela Pamfil, Alina-Diana Panainte, Gladiola Tantaru, Madalina-Alexandra Vlad, Claudiu N Lungu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andreea CreteanuDepartment of Pharmaceutical Technology, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iași, Romania.
Gabriela LisaDepartment of Chemical Engineering, Faculty of Chemical Engineering and Environmental Protection, "Gheorghe Asachi" Technical University, 73 Prof. Dimitrie Mangeron, Street, 700050 Iași, Romania.ORCID 0000-0002-4541-7446
Cornelia VasilePhysical Chemistry of Polymers Department, Petru Poni Institute of Macromolecular Chemistry, 41A Gr. Ghica Voda Alley, 700487 Iași, Romania.ORCID 0000-0003-1854-0278
Maria-Cristina PopescuPhysical Chemistry of Polymers Department, Petru Poni Institute of Macromolecular Chemistry, 41A Gr. Ghica Voda Alley, 700487 Iași, Romania.ORCID 0000-0003-4543-2870
Daniela PamfilPhysical Chemistry of Polymers Department, Petru Poni Institute of Macromolecular Chemistry, 41A Gr. Ghica Voda Alley, 700487 Iași, Romania.
Alina-Diana PanainteDepartment of Analytical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iași, Romania.ORCID 0000-0001-5255-2737
Gladiola TantaruDepartment of Analytical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iași, Romania.
Madalina-Alexandra VladDepartment of Microbiology, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iași, Romania.
Claudiu N LunguDepartment of Functional and Morphological Science, Faculty of Medicine and Pharmacy, Dunarea de Jos University, 800008 Galati, Romania.ORCID 0000-0002-5416-3142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, the application of lignin (LIG) as a bioactive additive for the preparation of drug-loaded tablets by direct compression has been studied, and its influence on the release of chlorzoxazone (CLZ) from the hydrophilic matrices has been followed. In hydrophilic matrices, the excipients Kollidon

Indexed as

Anti-Infective AgentsAntioxidantsChlorzoxazoneDrug LiberationExcipientsLigninCandida albicansChitosanEscherichia coliKlebsiellaPhytochemicalsPovidoneSpectroscopy, Fourier Transform InfraredStaphylococcus aureusTabletsX-Ray DiffractionAnti-Infective AgentsAntioxidantsChitosanChlorzoxazoneExcipientsLigninPhytochemicalsPovidoneTabletsantimicrobial propertiesantioxidantchlorzoxazoneligninmatrix tablets

Identifiers

PMID40286006
PMCPMC11990326

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.