ArticleMolecules (Basel, Switzerland)2025
Indocyanine Green-Loaded Quenched Nanoliposomes as Activatable Theranostics for Cancer.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Optical-thermal modeling and treatment planning of ICG-enhanced interstitial photothermal therapy using cylindrical diffuser fibers.Lasers in medical science · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Photodynamic therapy (PDT) and photothermal therapy (PTT) are considered to be one of the most effective methods for treating cancer due to their noninvasive nature, high effectiveness, and fewer side effects compared to standard therapeutic modalities for cancer. However, conventional always-on types of PDT and PTT agents have basic drawbacks in their in vivo applications, which include the unwanted generation of strong fluorescence signals and phototoxicity in normal tissues, including blood vessels, when exposed to light, resulting in poor imaging contrast and unwanted phototoxicity. Here, we propose indocyanine green-loaded quenched nanoliposomes (Q-ICG-NLs) as an activatable nanotheranostics. Q-ICG-NLs showed significant quenching in near-infrared fluorescence emission and singlet oxygen generation upon light irradiation. The photothermal effect of Q-ICG-NLs was 1.3 times greater than free indocyanine green. Its fluorescence and singlet oxygen generation were largely restored when taken up into cancer cells, enabling the selective detection and phototherapy of cancer cells. These results suggest that Q-ICG-NLs can be effectively used for selective near-infrared fluorescence imaging and the subsequent image-guided PDT and PTT of cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.