Evidence map›Paper›PMID 40286249›Full record

ArticleMolecules (Basel, Switzerland)2025

Synthesis of 2-Amino-4, 5-Diarylthiazole Derivatives and Evaluation of Their Anti-

Dongmei Gao, Lele Shi, Yuhang Huang, Yingmei Lv, Xuan Yang, Zhenting Du

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongmei GaoYangling Vocational & Technical College, Yangling 712100, China.ORCID 0009-0004-9655-4522
Lele ShiSchool of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.
Yuhang HuangSchool of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.
Yingmei LvSchool of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.
Xuan YangSchool of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.
Zhenting DuSchool of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.ORCID 0000-0001-5472-9815

Funding

Yangling Demonstration Zone 2024NY-29
6 · The paper itself

Abstract

The thiazole heterocycle is one of the most common moieties found in various drugs. Using 2-aminothiazole as the core structure, the amino group was functionalized with an amide. As a result, 30 trisubstituted 2-amino-4, 5-diarylthiazole derivatives were synthesized, with different substitutions introduced at the C2, C4, and C5 positions. The anti-

Indexed as

Antifungal AgentsCandida albicansThiazolesFungal ProteinsMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntifungal AgentsFungal ProteinsThiazoles2-Amino-4, 5-diarylthiazoleanti-Candida albicans activitymolecular docking

Identifiers

PMID40286249
PMCPMC11990618

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.