Evidence map›Paper›PMID 40287622›Full record

ArticleBMC gastroenterology2025

Global, regional, and national burden of disease analysis on paralytic ileus and intestinal obstruction in adults aged 65 and over from 1990 to 2021, with projections for 2030: a Global Burden of Disease Study 2021 analysis.

Tao Zhang, Meng Chen, Zhitong Yu, Zhetan Ren, Ling Wang, Qi Si, Xinping Lu, Siyuan Bu, Sihong Shen, Qingyan Wang and 1 more

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PubMed Full text at PMC Publisher
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Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tao ZhangLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Meng ChenThird Affiliated Hospital, Liaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Zhitong YuLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Zhetan RenDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100000, China.
Ling WangLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Qi SiLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Xinping LuLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Siyuan BuLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Sihong ShenLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China.
Qingyan WangLiaoning University of Traditional Chinese Medicine, Shenyang, 110000, China. wangqingyan2019@163.com.
Yongduo YuSecond Affiliated Hospital, Liaoning University of Traditional Chinese Medicine, Shenyang, 110000, China. yuyongduo@163.com.

Funding

Basic Research Projects of Liaoning Provincial Department of Science and Technology for Universities 2024-JYTCB-071Key R&D Program Project of Liaoning Province 2023JH2/101300100Liaoning Province's "Xingliao Talent Plan" project XLYC2002002
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the burden and trends of paralytic ileus and bowel obstruction in individuals aged ≥ 65 years, offering insights into prevention, treatment, and healthcare policy.

methodsData from the Global Burden of Disease Study 2021 were used to analyze paralytic ileus and intestinal obstruction by demographics, year, country/region, and Socio-Demographic Index (SDI). The statistical methods included Joinpoint regression, decomposition analysis, and Bayesian Age-Period-Cohort modeling.

resultsIn 2021, the global age-standardized incidence of paralytic ileus and intestinal obstruction among the elderly was 643.45 cases per 100,000 individuals. The corresponding prevalence was 24.05 per 100,000 individuals, with disability-adjusted life years (DALYs) of 294.01 per 100,000 person-years and a mortality rate of 20.55 per 100,000 individuals. Between 1990 and 2021, the age-standardized incidence and prevalence of paralytic ileus and intestinal obstruction in the elderly gradually increased, while age-standardized DALYs and mortality consistently declined. Despite similar trends observed across both genders, the disease burden increased with age and was more pronounced in males than in females. Furthermore, the age-standardized incidence and prevalence of these conditions increased with SDI, whereas mortality and DALYs decreased. By 2030, the incidence and prevalence are expected to continue increasing, whereas mortality and DALYs are expected to decrease.

conclusionsDespite the consistent decrease in mortality and DALYs associated with paralytic ileus and bowel obstruction in the elderly population aged ≥ 65 years, their incidence and prevalence continue to increase annually. This underscores the importance of improving preventive measures, early screening, and treatment efforts to address this pressing public health challenge.

Indexed as

Global Burden of DiseaseIntestinal ObstructionIntestinal Pseudo-ObstructionAgedAged, 80 and overBayes TheoremDisability-Adjusted Life YearsFemaleGlobal HealthHumansIncidenceMalePrevalenceDisease burdenOlder adultsParalytic ileus and intestinal obstructionProjectionsTrend analysis

Identifiers

PMID40287622
PMCPMC12032820

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.