ArticleNutrition journal2025
Efficacy of structured exercise and oat supplementation for treating non-alcoholic fatty liver disease: protocol of a randomized controlled trial.
Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
backgroundLifestyle modifications, including nutritional therapy and physical activity, are recommended as a first-line treatment for non-alcoholic fatty liver disease (NAFLD). However, both the best dietary approach and the optimal exercise pattern remain controversial. We will assess the efficacy of structured exercise and oats supplementation in NAFLD patients. METHODS/
designParticipants aged 18-65 years with intrahepatic lipid content ≥5% according to quantitative computed tomography (QCT) (N = 180) will be included in this randomized controlled 24-week structured exercise and dietary intervention study. Eligible participants will be randomly assigned (1:1:1:1) to the structured exercise group (aerobic exercise and resistance training), diet intervention group (80 g oats/daily supplementation), combined group (structured exercise + diet intervention) or control group. All participants will receive routine lifestyle education based on their daily caloric intake. The primary outcome was the change in the intrahepatic lipid content in the four groups. Body composition, muscle strength, and 72-hour dietary records will be assessed, and blood, urine and faeces tissue samples at baseline and at 12 and 24 weeks will be collected. Data will be analysed using t tests or Wilcoxon rank sum tests to compare the changes in the outcome measures among the different groups. DISCUSSION: There are limited data on the efficiency of structured exercise and oat supplementation for NAFLD treatment. The findings of this study will provide evidence-based data to health providers on lifestyle interventions aimed at alleviating the current NAFLD epidemic.
trial registrationThe study was registered with the Chinese Clinical Trial Registry (ChiCTR2100048042) on June 28, 2021.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.