Evidence map›Paper›PMID 40289301›Full record

ReviewCancer medicine2025

Diagnosis and Treatment of Primary Tracheobronchial Tumors.

Chen Shu, Yu-Jian Liu, Kai-Fu Zheng, Xi-Yang Tang, Meng-Chao Li, Yang Shen, Yu-Long Zhou, Wei-Guang Du, Nan Ma, Jin-Bo Zhao

Abstract readReview
In one paragraph

Review in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chen ShuDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0009-0002-5885-3519
Yu-Jian LiuDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Kai-Fu ZhengDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Xi-Yang TangDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Meng-Chao LiDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Yang ShenDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Yu-Long ZhouDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Wei-Guang DuDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Nan MaDepartment of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University, Shaanxi, China.
Jin-Bo ZhaoDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-7806-6072

Funding

the Certificate of China Postdoctoral Science Foundation Grant 2024M754284the National Natural Science Foundation of China 82070101the Natural Science Foundation of Hubei Province 2024AFB541
6 · The paper itself

Abstract

backgroundPrimary tracheobronchial tumors (PTBTs) are rare but life-threatening, accounting for approximately 0.2% of all respiratory neoplasms. Owing to their nonspecific clinical symptoms, PTBTs are often initially misdiagnosed as bronchial asthma or bronchitis in the early stages. In addition, standardized treatments for PTBTs are currently lacking.

aimsThis study aimed to provide a comprehensive review of this diagnostic challenge and treatment modalities of PTBTs.

methodsDrawing on the latest literature and clinical guidelines, we carried out a comprehensive and systematic analysis of PTBTs, focusing on diagnostic modalities, and evidence-based treatment options. RESULTS AND

conclusionsPrimary diagnostic methods for PTBTs include pulmonary function tests, chest radiography, computed tomography, and fiberoptic bronchoscopy. Computed tomography, and fiberoptic bronchoscopy may be the most valuable diagnostic tools for patients with PTBTs or those highly suspected of having PTBTs. Currently, there are no consensus guidelines for PTBTs, and surgery is the most effective method for treating PTBTs if the patients have indications for surgery. In addition, radiotherapy, chemotherapy and interventional therapy may be useful complementary treatments for inoperable patients. Immunotherapy may be a significant management strategy for PTBTs in the future. Further researches should concentrate on both the early identification and enhanced therapeutic management of these tumors to improve survival and diminish morbidity and mortality rates by investigating the optimal design of systematic therapy.

Indexed as

Bronchial NeoplasmsTracheal NeoplasmsBronchoscopyHumansTomography, X-Ray Computeddiagnosisimmunotherapyprimary tracheobronchial tumorssurgical treatmenttracheal reconstruction

Identifiers

PMID40289301
PMCPMC12034573

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.