Evidence map›Paper›PMID 40289329›Full record

ArticleEndocrinology, diabetes & metabolism2025

Hyperglycaemia and Its Risk Factors Among Adults Living With HIV on Follow-Up at the Hawassa City Administration, Southern Ethiopia: A Cross-Sectional Study.

Agete Tadewos Hirigo, Daniel Yilma, Ayalew Astatkie, Zelalem Debebe

Abstract read
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Article in Endocrinology, diabetes & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Agete Tadewos HirigoSchool of Medical Laboratory Science, College of Medicine Health Sciences, Hawassa University, Hawassa, Ethiopia.ORCID https://orcid.org/0000-0001-8426-051X
Daniel YilmaDepartment of Internal Medicine, College of Public Health and Medical Sciences, Jimma University, Jimma, Ethiopia.
Ayalew AstatkieSchool of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Zelalem DebebeCenter for Food Science and Nutrition, Addis Ababa University, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEthiopia implemented the universal test and treat in 2017 and later adopted dolutegravir-based regimens for people living with HIV (PLWH). However, the impact of these changes on glucose metabolism in Ethiopia remains unclear, highlighting the need for further investigation.

methodsA cross-sectional study was conducted in southern Ethiopia from 5 January 2023 to 30 May 2024. We included 443 adult PLWH using systematic random sampling. American Diabetes Association criteria was used to define hyperglycaemia. To identify factors associated with hyperglycaemia, binary logistic regression was used with adjusted odds ratio (AOR) and 95% confidence interval (CI).

resultsOverall prevalence of hyperglycaemia was 24.4% (16.7% prediabetes and 7.7% diabetes mellitus [DM]). Of the participants with DM, 82.3% were newly diagnosed. Significant predictors of hyperglycaemia were age > 50 years (AOR 2.1; 95% CI 1.1-3.9), alcohol intake (AOR 2.1; 95% CI 1.02-4.2), obesity (AOR 3.2; 95% CI 1.3-7.9), high waist-hip ratio (AOR 2.6; 95% CI 1.4-5.05) and LDL-cholesterol (AOR 2.2; 95% CI 1.02-4.6). While significant predictors of DM were alcohol intake (AOR 3.0; 95% CI 1.1-8.4), co-morbidity (AOR 2.6; 95% CI 1.1-6.05), high waist circumference (AOR 7.5; 95% CI 1.3-43.3), high waist-hip ratio (AOR 4.1; 95% CI 1.02-16.2) and high triglycerides (AOR 3.2; 95% CI 1.3-7.7). Dolutegravir-based regimen was not associated with hyperglycaemia.

conclusionHyperglycaemia prevalence among adult PLWH on antiretroviral therapy in southern Ethiopia is rising, with most diabetes cases newly identified. This emphasises the critical need for routine screening to enable early detection, prevention and management.

Indexed as

HIV InfectionsHyperglycemiaAdultCross-Sectional StudiesEthiopiaFemaleFollow-Up StudiesHumansMaleMiddle AgedPrevalencePyridonesRisk FactorsYoung AdultPyridonesantiretroviral therapydiabetes mellitusdolutegravirHIVprediabetessouthern Ethiopiaundiagnosed diabetes

Identifiers

PMID40289329
PMCPMC12034571

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.