Evidence map›Paper›PMID 40289758›Full record

ArticleThe Kaohsiung journal of medical sciences2025

LncRNA PVT1 Facilitates Phenotypic Switching of Vascular Smooth Muscle Cells in Intracranial Aneurysms by Recruiting KDM1A to Reduce H3K9me2 Modification.

Yu-Fei Cheng, Wei Sun, Yi-Xia Wang, Jia-Jie Chen, Ya-Sen Cao

Abstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Fei ChengYangzhou University Medical College, Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0009-0003-1871-6090
Wei SunYangzhou University Medical College, Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.
Yi-Xia WangYangzhou University Medical College, Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.
Jia-Jie ChenYangzhou University Medical College, Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.
Ya-Sen CaoYangzhou University Medical College, Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the differential expression of lncRNA PVT1 in intracranial aneurysms (IAs) and its role in the phenotypic switching of vascular smooth muscle cells (VSMCs). PVT1 and ALOX5 expressions in the serum of IA patients and healthy controls were detected by qRT-PCR. The diagnostic efficacy of PVT1 for IA was analyzed using the receiver operating curve (ROC). VSMCs were treated with H

Indexed as

Histone DemethylasesHistonesIntracranial AneurysmMuscle, Smooth, VascularMyocytes, Smooth MuscleRNA, Long NoncodingFemaleHumansMaleMiddle AgedPhenotypeHistone DemethylasesHistonesKDM1A protein, humanPVT1 long-non-coding RNA, humanRNA, Long NoncodingALOX5intracranial aneurysmsKDM1ALncRNA PVT1vascular smooth muscle cells

Identifiers

PMID40289758
PMCPMC12412498

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.