Evidence map›Paper›PMID 40289995›Full record

ReviewNutrients2025

Nutrition, Lifestyle, and Environmental Factors in Lung Homeostasis and Respiratory Health.

Athanasios Pouptsis, Rosa Zaragozá, Elena R García-Trevijano, Juan R Viña, Elena Ortiz-Zapater

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Athanasios PouptsisDepartment of Biochemistry and Molecular Biology-INCLIVA, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-9469-6069
Rosa ZaragozáDepartment of Human Anatomy and Embryology-INCLIVA, University of Valencia, 46010 Valencia, Spain.
Elena R García-TrevijanoDepartment of Biochemistry and Molecular Biology-INCLIVA, University of Valencia, 46010 Valencia, Spain.
Juan R ViñaDepartment of Biochemistry and Molecular Biology-INCLIVA, University of Valencia, 46010 Valencia, Spain.
Elena Ortiz-ZapaterDepartment of Biochemistry and Molecular Biology-INCLIVA, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-7437-4772

Funding

Spanish Ministry of Science and Innovation PID2023-149201OB-I00
6 · The paper itself

Abstract

The lungs play a vital role in maintaining homeostasis by facilitating gas exchange and serving as a structural and immune barrier. External factors, including nutrition, lifestyle, and environmental exposures, profoundly influence normal lung function and contribute to the development, progression, and prognosis of various respiratory diseases. Deficiencies in key micronutrients, such as vitamins A, D, and C, as well as omega-3 fatty acids, can impair the integrity of the epithelial lining, compromising the lungs' defense mechanisms and increasing susceptibility to injury and disease. Obesity and physical inactivity further disrupt respiratory function by inducing structural changes in the chest wall and promoting a pro-inflammatory state. Environmental pollutants further worsen oxidative damage and activate inflammatory pathways. Addressing these modifiable factors through interventions such as dietary optimization, physical activity programs, and strategies to reduce environmental exposure offers promising avenues for preserving lung function and preventing disease progression. This review examines the molecular pathways through which nutrition, lifestyle, and environmental influences impact lung homeostasis.

Indexed as

Environmental ExposureHomeostasisLife StyleLungNutritional StatusExerciseHumanschrono nutritiondiethomeostasislifestylelungsmetabolismmicronutrientspollutantsrespiratory function

Identifiers

PMID40289995
PMCPMC11944992

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.