ArticlePakistan journal of medical sciences2025
Percutaneous Kyphoplasty combined with different anti-osteoporosis drugs for the treatment of osteoporotic vertebral compression fractures.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Objective: To explore the effectiveness of percutaneous kyphoplasty (PKP) combined with different anti-osteoporosis drugs in the treatment of osteoporotic vertebral compression fractures (OVCF) by assessing bone mineral density, pain, lumbar functional recovery, and incidence of vertebral refractures after the combined therapy. Methods: In this single-center retrospective study, medical records of 138 patients with OVCF who underwent PKP in the Third Hospital of Hebei Medical University between January 2021 and October 2022 were retrospectively analyzed. Among them, 41 patients treated with calcium and alfacalciferol supplementation after PKP (Group-A), 58 patients treated with calcium and calcitonin after PKP (Group-B), and 39 patients treated with calcium, calcitonin, and alendronate sodium after PKP (Group-C). Bone mineral density, pain, lumbar functional recovery, and incidence of vertebral refractures in the three groups were compared before and after PKP. Results: At six and 12 months after PKP, bone density T-values of Group-B and Group-C were significantly higher than Group-A (P<0.05). The visual analogue scale (VAS) scores of Group-B and Group-C were significantly lower than Group-A ( Conclusions: In the treatment of osteoporotic vertebral compression fractures after percutaneous kyphoplasty, a combination of calcium therapy with calcitonin and alendronate sodium had a positive effect, which may effectively improve bone density, pain, and functional status, and reduce the incidence of vertebral body fractures.
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