ArticleFrontiers in nutrition2025
Depression and diabetic retinopathy: an underexplored connection.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bidirectional relationship of diabetic retinopathy with anxiety and depression: a meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Vision-Focused Nomogram for Assessing the Risk of Depression in Diabetic Retinopathy: Integrating Visual Function, Metabolic Factors and Psychosocial Status.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Linking diabetic retinal changes with the occurrence of anxiety and depression in working population.Open medicine (Warsaw, Poland) · 2026Article
- The triglyceride-glucose index for diabetic retinopathy prediction in Chinese patients with type 2 diabetes: a preliminary cross-sectional study.Frontiers in endocrinology · 2026Article
- Non-linear association between Life's Essential 8 and diabetic retinopathy: mediating role of depression in US adults with diabetes.BMC public health · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Background: Diabetic retinopathy, a major microvascular complication of diabetes, significantly contributes to global blindness. Emerging evidence suggests a potential association between depression and DR, yet the mechanisms remain unclear. Objectives: This study aimed to investigate the relationship between depression and DR using nationally representative data from the National Health and Nutrition Examination Survey (NHANES, 2011-2020). Methods: Depression was assessed using the PHQ-9, and DR was identified through self-reported diagnoses. Multivariable logistic regression and restricted cubic splines analyzed the relationship, adjusting for demographic and clinical covariates. Subgroup analyses examined interactions with factors like age and lipid control. Results: Among 1,653 participants, the weighted DR prevalence was 18.91%. Depression was independently associated with higher DR risk (OR: 1.69, 95% CI: 1.08-2.64, Conclusion: Depression is a significant and independent risk factor for DR, emphasizing the need for integrated management of mental health and metabolic control in diabetic patients. Addressing depression may reduce DR burden and improve overall quality of life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.