Evidence mapPaperPMID 40290665Full record

ArticleFrontiers in nutrition2025

Association between triglyceride-glucose index and sarcopenic obesity in adults: a population-based study.

Zhengmei Zhao, Ruiting Cai, Lili Tao, Yuxiao Sun, Keping Sun

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In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhengmei Zhao *Department of Geriatrics, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Ruiting Cai *Department of Geriatrics, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Lili Tao *Department of Geriatrics, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Yuxiao SunDepartment of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Keping SunDepartment of Geriatrics, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sarcopenic obesity is characterized by the coexistence of sarcopenia and obesity, which has been demonstrated to be linked to insulin resistance. The triglyceride-glucose (TyG) index is a novel surrogate indicator of insulin resistance. However, the relationship between sarcopenic obesity and the TyG index remains unclear. This population-based study aimed to investigate the association between TyG index and sarcopenic obesity in adults. Methods: This study utilized data from the China Health and Retirement Longitudinal Study (CHARLS), individuals aged over 45 years were categorized into sarcopenia, obesity, sarcopenic obesity, and control groups. Baseline characteristics were analyzed across these groups. Logistic regression models were employed to explore the association between the TyG index and sarcopenic obesity, adjusting for confounding variables. Subgroup analyses were conducted to explore the potential variations in this association across different demographic and clinical variables. Results: A total of 9,485 individuals were included in the study, with the sarcopenic obesity group exhibiting a higher TyG index (8.96 ± 0.61) compared to other groups ( Conclusion: The findings suggest a strong association between elevated TyG index and sarcopenic obesity in adults, independent of demographic and clinical factors. Further large-scale prospective studies are warranted to validate and expand upon these findings.

Indexed as

CHARLS databaseinsulin resistancepopulation-based studysarcopenic obesitytriglyceride-glucose index

Identifiers

PMID40290665
PMCPMC12021607

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.