Evidence map›Paper›PMID 40291226›Full record

ReviewCureus2025

Future of Sclerotherapy in the Treatment of Endometriosis: A Narrative Literature Review.

Dimitrios Lentzaris, Fani Gkrozou, Chara Skentou, Nikoleta Koutalia, Vasileios Bais, Anastasia Vatopoulou, Minas Paschopoulos

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dimitrios LentzarisObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Fani GkrozouObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Chara SkentouObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Nikoleta KoutaliaObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Vasileios BaisObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Anastasia VatopoulouObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.
Minas PaschopoulosObstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a gynaecological condition affecting reproductive-age women. In case of ovarian endometriosis, there is cystic formation, called endometrioma. Although laparoscopic cystectomy is established as the gold standard for the treatment of endometriomas, it is related to damage of healthy ovarian tissue and significant decrease in ovarian reserve. As a result, new strategies have been set for the care of endometriomas, with ethanol sclerotherapy as the most popular alternative. As a part of sclerotherapy, ethanol solution is injected to destroy pseudocapsule. Iatrogenic damage is minimized, making it a safe and less invasive technique. In this study, we compared ultrasound-guided (U/S) ethanol sclerotherapy and laparoscopic ethanol sclerotherapy with laparoscopic cystectomy. Anti-Müllerian hormone (AMH) is used to monitor ovarian preservation. Sclerotherapy seems to have smaller effect on ovarian reserve compared to cystectomy. Recurrence rate and clinical pregnancy rate are similar, though cystectomy has better outcome of symptom relief. Moreover, laparoscopic sclerotherapy seems to achieve the best clinical pregnancy rate and decrease recurrence rate.

Indexed as

cystectomyendometriomasendometriosisfertility preservationovarian cystsovarian reservesclerotherapy

Identifiers

PMID40291226
PMCPMC12022720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.