ReviewCureus2025
Impact of Diets on Cognitive and Clinical Outcomes in Alzheimer's Disease: A Scoping Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is characterized by beta-amyloid plaques and neurofibrillary tangles, leading to damage of neuronal synapses, negatively impacting memory and cognition. Research efforts have shown the benefit of proper nutrition in reducing the progression of AD and slowing the condition's progression. Specifically, nutritional intake has been demonstrated to influence neuro-inflammatory pathways. Various diets, including ketogenic, Mediterranean, Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, and Dietary Approaches to Stop Hypertension (DASH), have been shown to prevent the onset of AD to different degrees. The primary objective of this scoping review was to assess the impacts of various diets on AD onset and progression to identify unmet needs and gaps in understanding. Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, peer-reviewed literature was searched using Boolean operators: "Alzheimer's" AND "ketogenic" OR "DASH diet" OR "MIND diet" OR "Mediterranean diet" on EMBASE, MEDLINE, and Web of Science databases. The search was restricted to articles written in English and published in the United States between January 1, 2013, and September 30, 2023. The initial search yielded 121 articles after removing duplicates. After filtering based on inclusion and exclusion criteria, 24 articles were selected for further critical appraisal screening. The critical appraisal yielded 12 articles for the analysis included in this scoping review. This review supported the Mediterranean diet as the most effective in improving outcomes among patients with AD. The Mediterranean diet consists of a high intake of vegetables, fruits, legumes, nuts, olive oil, and unrefined cereals, a moderate intake of fish and wine, and a low intake of dairy products, meat, poultry, and saturated fat. Other diets reviewed, including the DASH and MIND diets, also have promising effects on AD, with less conclusive evidence when compared to the Mediterranean diet. Limitations, including small sample sizes, short durations, and socioeconomic constraints impacting compliance, were noted. This scoping review supports the need for dietary recommendation guidelines for patients with AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.