Evidence map›Paper›PMID 40291783›Full record

ArticleOpen life sciences2025

Sodium butyrate aids brain injury repair in neonatal rats.

Jing Zhao, Jun Zhang, Can Yang, Linlin Yin, Li Hou, Lin Jiang

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing ZhaoDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, No. 1, Mao Yuan South Road, Shunqing District, Nanchong, Sichuan, 637000, China.
Jun ZhangDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.
Can YangDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.
Linlin YinDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.
Li HouDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.
Lin JiangDepartment of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate the effects and mechanism of action of sodium butyrate (SB) on brain injury repair in neonatal rats. 126 neonatal SD rats were randomly allocated to 7 groups, and necrotizing enterocolitis (NEC) and hypoxic-ischemic brain injury (HIBI) rat models were established. Hematoxylin and eosin staining showed that SB intervention alleviated intestinal and brain injuries in the HIBI + SB, NEC + SB, and NEC + HIBI + SB groups. Compared to the NEC and NEC + HIBI groups, the NEC + SB and NEC + HIBI + SB groups had significantly higher interleukin (IL)-10 and lower IL-17 levels (

Indexed as

brain injurygut-brain axisgut microbiotaneonatal ratssodium butyrate

Identifiers

PMID40291783
PMCPMC12032984

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.