Evidence map›Paper›PMID 40291900›Full record

ArticleWorld journal of gastrointestinal surgery2025

Comparison of the efficacy of carbapenems and cephalosporins for postoperative treatment of perforated appendicitis in children.

Tian Hang, Qiao-Lin Chen, Ya-Hong Li, Shi-Wen Wang, Xiao-Hong Jiang, Wei-Chao Zhu

Abstract read
In one paragraph

Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tian HangDepartment of Pediatric Surgery, Jiaxing Maternity and Child Health Care Hospital, Jiaxing 314009, Zhejiang Province, China.
Qiao-Lin ChenDepartment of Pediatric Surgery, The First Affiliated Hospital of Ningbo University, Ningbo 315010, Zhejiang Province, China.
Ya-Hong LiDepartment of Pediatric Surgery, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China.
Shi-Wen WangDepartment of Pediatric Surgery, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China.
Xiao-Hong JiangDepartment of Pathology, Jiaxing Women and Children Hospital affiliated to Jiaxing University, Jiaxing 314009, Zhejiang Province, China.
Wei-Chao ZhuDepartment of Pediatric Surgery, The First Affiliated Hospital of Ningbo University, Ningbo 315010, Zhejiang Province, China. fyzhuweichao@nbu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric perforated appendicitis (PPA) is a severe acute condition requiring surgical intervention and postoperative antibiotic therapy. Antibiotic selection differs significantly among pediatric centers, and an ideal postoperative anti-infective approach for PPA management has yet to be established.

aimTo examine the spectrum of pathogenic bacteria in pediatric PPA and to summarize the postoperative experience with carbapenem (CBP) and cephalosporin (CPS) antibiotics.

methodsWe retrospectively analyzed medical records of 65 children (43 boys, 22 girls; mean age 6.92 ± 3.41 years) with PPA who underwent surgery at our hospital between December 2019 and August 2022. Data were collected in September 2023. Based on postoperative antibiotic selection, patients were divided into CBP (32 cases) and CPS (33 cases) groups. Chi-square and T-tests compared recovery outcomes, while univariate and multivariate regression models identified independent factors affecting postoperative recovery.

resultsThere were no significant differences between the two groups in gender, age, weight, height, body mass index, baseline ear temperature, or heart rate (

conclusionThe choice of CBP or CPS independently affects CRP recovery within 7 days. CBP offers no advantage over CPS in treating PPA, with CPS also demonstrating favorable clinical outcomes.

Indexed as

CarbapenemsCephalosporinsChildrenPathogenic bacteriaPerforated appendicitis

Identifiers

PMID40291900
PMCPMC12019071

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.