Evidence map›Paper›PMID 40292204›Full record

ReviewSleep science (Sao Paulo, Brazil)2025

Obstructive Sleep Apnea Endophenotypes.

Janna Rae Raphelson, Ana Lucia Fuentes, Breanna Holloway, Atul Malhotra

Abstract readReview
In one paragraph

Review in Sleep science (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Sleep apnea, how do we help thee? Let us count the ways.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janna Rae RaphelsonSchool of Medicine, University of California San Diego, La Jolla, CA, United States.
Ana Lucia FuentesSchool of Medicine, University of California San Diego, La Jolla, CA, United States.
Breanna HollowaySchool of Medicine, University of California San Diego, La Jolla, CA, United States.
Atul MalhotraSchool of Medicine, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-9509-1827

Funding

The Left and Right Ventricles in Sleep Apnea with COPDF32HL176079 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAPHELSON, JANNA · 2024 to 2025
$167k
NHLBI NIH HHS F32 HL176079NHLBI NIH HHS L30 HL175771
6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a common disorder with major neurocognitive and cardiometabolic consequences. It is now recognized as a heterogeneous disease with multiple different underlying mechanisms (endotypes) as well as variable clinical expression of disease (phenotypes). The importance of this variability is emphasized since one variable in isolation typically explains only a fraction of the variance in OSA occurrence. This review provides an update of what is known regarding OSA heterogeneity. The importance of OSA endotypes is discussed in the context of how mechanism might affect disease management and/or design of subsequent randomized trials. Further research is recommended to provide further validation of OSA endophenotypes and how this information may influence clinical management in the future.

Indexed as

arousalhypoxemialungsleep

Identifiers

PMID40292204
PMCPMC12020574

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.