Evidence map›Paper›PMID 40293492›Full record

Trial reportRheumatology international2025

RhePort 1.3 enhances early identification of inflammatory rheumatic diseases: a prospective study in German rheumatology settings.

Cay-Benedict von der Decken, Stefan Kleinert, Matthias Englbrecht, Kirsten Karberg, Georg Gauler, Monika Ronneberger, Praxedis Rapp, Florian Schuch, Joerg Wendler, Susanna Späthling-Mestekemper and 4 more

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cay-Benedict von der DeckenRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany. c.vonderdecken@rhadar.de.ORCID http://orcid.org/0000-0001-9780-7174
Stefan KleinertRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0002-2588-7547
Matthias EnglbrechtFreelance Healthcare Data Scientist, Greven, Germany.ORCID http://orcid.org/0000-0003-0228-7183
Kirsten KarbergRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0002-1362-7326
Georg GaulerRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0002-2132-8369
Monika RonnebergerPraxisgemeinschaft Rheumatologie-Nephrologie, Erlangen, Germany.ORCID http://orcid.org/0009-0007-1929-8977
Praxedis RappPraxisgemeinschaft Rheumatologie-Nephrologie, Erlangen, Germany.ORCID http://orcid.org/0009-0003-9257-1707
Florian SchuchPraxisgemeinschaft Rheumatologie-Nephrologie, Erlangen, Germany.ORCID http://orcid.org/0000-0002-2543-0491
Joerg WendlerPraxisgemeinschaft Rheumatologie-Nephrologie, Erlangen, Germany.ORCID http://orcid.org/0009-0009-4167-8989
Susanna Späthling-MestekemperRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0009-0008-8124-2111
Christoph KuhnRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0002-0538-1717
Wolfgang VorbrüggenRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0003-1076-5560
Martin WelckerRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0002-1856-3085
Peter Bartz-BazzanellaRHADAR-RheumaDatenRheport GbR, Möhrendorfer Str. 1 C, 91056, Erlangen, Germany.ORCID http://orcid.org/0000-0001-8084-4497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More efficient means of identifying patients with inflammatory rheumatic diseases (IRDs) could allow earlier diagnosis and treatment. The objective of this study was to evaluate the characteristics of a revised version of an online patient questionnaire-based self-referral tool, RhePort 1.3. This prospective study included adult patients with musculoskeletal complaints presenting for a first rheumatology visit at German RheumaDatenRhePort (RHADAR) rheumatology network centers. All patients completed the RhePort 1.3 questionnaire on patient characteristics and symptoms. Data from RhePort 1.3 were compared with historical data from previous versions. Of 614 patients, 225 (36.6%) were diagnosed with an IRD by a rheumatologist and 164/225 IRD patients (72.9%) had a RhePort 1.3 score > 1, the cut-off point used to determine the need for rheumatologic evaluation. A score > 1 was associated with an approximately two-fold higher IRD risk (odds ratio [95% confidence interval] of 1.98 [1.39, 2.83] vs ≤ 1) and had good sensitivity (73%) and moderate specificity (42%). Among patients referred through a standard referral pathway (n = 283), RhePort 1.3 scores > 1 in addition to physician referral were associated with increases in rheumatology-diagnosed IRD rates from 33.2% (physician referral only) to 45.7%. RhePort 1.3 had higher accuracy than earlier versions (54% vs 35%). We conclude that modest changes to the RhePort questionnaire resulted in increased accuracy. A score > 1 was associated with a doubled risk for an IRD and higher IRD rates in physician-referred patients. These data suggest that RhePort has the potential to streamline the rheumatologist's workload and improve resource use. Further modifications are required to improve specificity.

Indexed as

Rheumatic DiseasesRheumatologyAdultAgedEarly DiagnosisFemaleGermanyHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesReferral and ConsultationReproducibility of ResultsSurveys and QuestionnairesOnline systemReferral and consultationRheumatic diseasesRheumatologySurveys and questionnairesWorkload

Identifiers

PMID40293492
PMCPMC12037674

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.