ArticleCancer research communications2025
Social-Environmental Burden Is Associated with Increased Colorectal Cancer Mortality in Metropolitan Detroit.
Article in Cancer research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Effect of Race and Tumor Subsite on Survival Outcome in Early- and Late-Onset Colorectal Cancer.Cancers · 2026Article
- County-level social, preventive care, and behavioral correlates of colorectal cancer mortality in the United States: a nationwide ecological analysis.Frontiers in oncology · 2026Article
- Evaluating the impact of neighborhood socioenvironmental burden on patient characteristics and survival in liver transplant recipients.Frontiers in transplantation · 2026Article
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Authors and funding
10 authors.
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Abstract
abstractNeighborhood quality affects both socioeconomic factors and exposure to carcinogenic environmental pollutants, but the impacts of these factors on racial disparities in colorectal cancer mortality are not well described. We used the Centers for Disease Control and Prevention Environmental Justice Index social vulnerability module, environmental burden module (EBM), and the combined social–environmental score (SER) to assess relationships with colorectal cancer mortality by race and age in the Metropolitan Detroit Cancer Surveillance System. Among 13,505 patients with colorectal cancer [9,727 non-Hispanic White (NHW) and 3,778 non-Hispanic Black (NHB)], EBM quartile 4 versus 1 was more strongly associated with mortality among NHB early-onset (EO) cases than NHW EO cases [NHB: HR = 1.98, 95% confidence interval (CI), 1.20–3.26; NHW: HR = 1.40, 95% CI, 0.88–2.25]. SER quartile 4 versus 1 was more strongly associated with colorectal cancer mortality in EO (NHB: HR = 1.76, 95% CI, 0.93–3.31; NHW: HR = 1.53, 95% CI, 0.79–2.96) compared with later-onset cases (NHB: HR = 1.15, 95% CI, 0.87–1.52; NHW: HR = 1.39, 95% CI, 1.17–1.65) regardless of race. These associations in EO cases were strongest in colon tumors versus rectal tumors (EO EBM: colon HR = 2.08, 95% CI, 1.24–3.48 vs. rectum HR = 1.03, 95% CI, 0.64–1.66; EO SER: colon HR = 2.57, 95% CI, 1.38–4.79 vs. rectum HR = 0.84, 95% CI, 0.48–1.45). These results suggest the combination of socio-environmental burdens contributes to age and racial disparities in colorectal cancer mortality in metropolitan Detroit. SIGNIFICANCE: Understanding the role of environmental justice in cancer survivorship could influence policy decisions, aiding intervention practices.
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