Evidence map›Paper›PMID 40295908›Full record

ArticleBMC cardiovascular disorders2025

Association of dietary index of gut microbiota with cardiovascular disease risk: new evidence from NHANES 2007-2018.

Jiameng Jin, Xingang Sun, Lihong Wang

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Long-term follow-up study on the impact of a gut microbiota-supportive diet on heart failure and mortality outcomes.International journal of cardiology. Cardiovascular risk and prevention · 2025
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiameng JinSecond Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xingang SunDepartment of Cardiology Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang Province, China. 17816890299@163.com.
Lihong WangDepartment of Cardiology Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang Province, China. wanglhnew@126.com.

Funding

LW was sponsored by Ten-thousand Talents Program of Zhejiang Province No. 2021R52025National Natural Science Foundation of China No. 81670447the Medicine and Health Project of Zhejiang Province No. 2023KY531the Traditional Chinese Medicine Program of Zhejiang Provincial No. 2022ZZ003, No. 2023ZL248, 2022ZB024
6 · The paper itself

Abstract

backgroundThe dietary index of gut microbiota (DI-GM) is a newly proposed index for assessing dietary quality, and studies on its association with cardiovascular disease (CVD) are limited. This study aimed to investigate the association between DI-GM and the prevalence of CVD.

methodsWe utilized data from the National Health and Nutrition Examination Survey (NHANES). Logistic regression analyses were performed to examine the association between DI-GM and CVD. Smoothed curve fitting was employed to explore potential nonlinear relationships. Additionally, subgroup analyses were conducted to assess the stability of the results.

resultsThe study included 22,590 participants, of whom 20,216 had no CVD and 2,374 had CVD. After adjusting for all covariates, the DI-GM score was significantly negatively associated with CVD risk, with a 4% reduction in CVD risk for each unit increase in DI-GM score (OR = 0.96, 95% CI: 0.94-0.99, P = 0.015). Notably, the highest DI-GM score group (6-12) had a 13% lower risk of CVD compared to the lowest DI-GM score group (0-3) (OR = 0.87, 95% CI: 0.76-1.00, P = 0.048).

conclusionThe research results indicate that a higher DI-GM score protects against CVD, providing crucial empirical support for dietary intervention strategies based on gut microbiota modulation. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Cardiovascular DiseasesDietDiet, HealthyGastrointestinal MicrobiomeAdultAgedCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedNutrition SurveysNutritive ValuePrevalenceProtective FactorsCardiovascular disease (CVD)Dietary Index of Gut Microbiota (DI-GM)Lipopolysaccharide (LPS)National health and nutrition examination survey (NHANES)

Identifiers

PMID40295908
PMCPMC12039086

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.