ArticleBMC women's health2025
Global burden of metabolic disorders among women of child-bearing age, 1990-2021: a population-based study1990-2021:.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maternal-to-Infant Transfer of Medications for Type 2 Diabetes Mellitus Via Breastmilk: A Systematic Review of Available Evidence and Clinical Guidelines.Clinical pharmacology and therapeutics · 2026Pooled it
- Global burden of thyroid cancer attributable to metabolic risk factors in women of reproductive age (20-49 years): a GBD 2021 cross-national analysis with projections to 2050.BMC women's health · 2025Article
- Global burden, regional disparities, and decomposition analysis of metabolic risk-attributable diseases among women of reproductive age: GBD 2021.BMC women's health · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundMetabolic disorders have a significant impact on the health of women of childbearing age (WCBA) but remain underemphasized. This study aims to assess the global, regional, and national burden of metabolic disorders in WCBA from 1990 to 2021.
methodsPrevalence, mortality, and disability-adjusted life years (DALYs) related to metabolic disorders in WCBA from 1990 to 2021 were obtained from the Global Burden of Disease (GBD) 2021. Annual percentage changes were calculated, and stratified analyses were conducted based on age, region, nation, and socio-demographic index levels to assess the distribution of metabolic disorders in WCBA.
resultsGlobally, the overall burden of metabolic disorders among WCBA has increased. In 2021, obesity (330.21 [148.37-518.36]) had the highest age-standardized DALYs rate, followed by hypertension (200.75 [154.67-245.47]), type 2 diabetes mellitus (175.11 [134.18-223.42]), hyperlipidemia (139.02 [101.32-173.61]), and non-alcoholic fatty liver disease (10.1 [7.17-13.92]). The most significant changes of the overall metabolic disorders burden in WCBA were observed in younger age groups. The burden of metabolic disorders was higher in less-developed regions.
conclusionsGiven the marked increase in the burden of metabolic disorders among younger WCBA, it is recommended that healthcare management be reinforced for this demographic. Furthermore, based on the varying burdens observed across regions, targeted metabolic interventions for WCBA should be tailored to local conditions.
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