Evidence mapPaperPMID 40296076Full record

ArticleJournal of orthopaedic surgery and research2025

Very high prevalence of osteosarcopenia in hip fracture patients: risk and protective factors.

Ronald Man Yeung Wong, Pui Yan Wong, Wai Wang Chau, Chaoran Liu, Ning Zhang, Wing Hoi Cheung

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Serum parathyroid hormone and risk of sarcopenia: a meta-analysis.Journal of orthopaedic surgery and research · 2025
    Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronald Man Yeung WongDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China. ronald.wong@cuhk.edu.hk.
Pui Yan WongDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Wai Wang ChauDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Chaoran LiuDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Ning ZhangDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Wing Hoi CheungDepartment of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.

Funding

Collaborative Research Fund, Research Grants Council C4032-21GFGeneral Research Fund, Research Grants Council 14116223
6 · The paper itself

Abstract

backgroundHip fractures are one of the most serious forms of osteoporotic fractures. Osteosarcopenia is a growing geriatric giant with increased risk of falls, fractures, disability and mortality. The objective of this cross-sectional study was to determine the prevalence and risk factors of osteosarcopenia amongst hip fracture patients.

methodsAll patients received a dual energy x-ray absorptiometry (DXA) scan for diagnosis of osteopenia and osteoporosis. For sarcopenia assessment, patients received a bioimpedance analysis (BIA) measurement, handgrip strength and 5-time chair stand test. Osteosarcopenia was defined with the presence of osteopenia/osteoporosis and sarcopenia. Risk factors for osteosarcopenia were analysed using logistic regression.

resultsA total of 342 hip fracture patients (n = 342) were recruited. Sarcopenia was present in 286 hip fracture patients (83.6%). 335 hip fracture patients (97.95%) had osteopenia/osteoporosis. Osteosarcopenia was present in 281 hip fracture patients (82.2%). For osteosarcopenia, patients with body mass index (BMI) < 23 kg/m

conclusionsOur study had shown a very high prevalence of osteosarcopenia amongst hip fracture patients, especially in male patients, and identified associated risk and protective factors. Given the potential clinical implications, we would recommend that in addition to bone mineral density assessment, routine sarcopenia assessment should also be incorporated into Fracture Liaison Services. Further research should be conducted on optimal body weight and BMI, and as to why male patients have more likelihood of sarcopenia.

Indexed as

Bone Diseases, MetabolicHip FracturesOsteoporotic FracturesSarcopeniaAbsorptiometry, PhotonAgedAged, 80 and overCross-Sectional StudiesFemaleHand StrengthHumansMaleMiddle AgedOsteoporosisPrevalenceProtective FactorsFracture liaison serviceHip fractureOsteoporotic fractureOsteosarcopenia

Identifiers

PMID40296076
PMCPMC12036194

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.