Evidence map›Paper›PMID 40296926›Full record

ArticleCureus2025

Extramedullary Hematopoiesis Presenting as Pleural Thickening in a Patient With Choroidal Melanoma.

Shuai Li, Anusha Mubin, David Cantu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shuai LiPathology, Creighton University School of Medicine, Omaha, USA.
Anusha MubinPathology, Creighton University School of Medicine, Omaha, USA.
David CantuPathology, Creighton University School of Medicine, Omaha, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extramedullary hematopoiesis (EMH), the generation of blood cells by organs other than the bone marrow, most often occurs in the spleen or liver. However, it has been known to uncommonly occur in other locations. EMH in these locations does not consistently manifest in the same way, making this a difficult diagnosis to make. We report the case of a 79-year-old male former smoker with a history of choroidal melanoma and polycythemia vera who presented with a chronic cough and weight loss of 30 pounds over the last year. A CT scan revealed a 15 mm right basilar pleural enhancement suspicious for malignancy on imaging. Upon biopsy, it was found that the pleural enhancement was EMH due to post-polycythemia vera myelofibrosis. EMH can be difficult to distinguish from metastasis, especially in atypical locations and in patients with a history of malignancy.

Indexed as

extramedullary hematopoiesishematopathologypathologypleural thickeningpolycythemia vera

Identifiers

PMID40296926
PMCPMC12037201

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.